General Information
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Product
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Stra6 Antibody
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Description
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Affinity Purified Retinoic acid-responsive protein Antibody
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Mouse, Rat
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Immunogen
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Synthetic peptide taken within third large intra cytoplasmic loop within amino acid region 200-300 on rat Stra6 protein.
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Accession #
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GenBank: AAC16016.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.69 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:10,000
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Immunohistochemistry |
1:100 |
Immunoprecipitation
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1:200
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Western Blot
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1:500
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Protein
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Uniprot #
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O70491
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Overview
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May act as a high-affinity cell-surface receptor for the complex retinol-retinol binding protein (RBP/RBP4). Acts by removing retinol from RBP/RBP4 and transports it across the plasma membrane, where it can be metabolized. This mechanism does not depend on endocytosis. Binds to RBP/RBP4 with high affinity.
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Molecular Function
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Receptor, Receptor activity
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Subcellular Location
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Cell membarane; Multi-pass membrane protein
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Expression
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Widely expressed in the embryo. In the adult, is highly expressed in cells that compose blood-organ barriers in the brain (choroid plexus and the brain microvascular), in the eye (retinal pigment epithelium), in testis (the basal layer of the seminiferous epithelium), in the yolk sac, and in the chorioallantoic placenta (at protein level). Also detected in kidney, spleen, and female genital tract; and at lower levels in heart and lung.
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Alternative Nomenclature
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MCOPCB8 antibody
MCOPS9 antibody
PP14296 antibody
Stimulated by retinoic acid 6 homolog antibody
STRA6 antibody
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