LYK5 Antibody

Product no.: STRAD-101AP

$285.00

Description
Specification Sheet

General Information
Product	LYK5 Antibody
Description	Affinity Purified STE20-related kinase adapter protein alpha Antibody N-epitope
Verified Applications	ELISA, IHC, IP, WB, Flowcytometry
Host	Rabbit
Species Cross Reactivity	Human, Monkey
Immunogen	Synthetic peptide taken within amino acid region 50-100 on human STE-20 related kinase adapter protein alpha.
Accession #	NCBI: NP_001003787.1
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.64-0.72 µg/µl in antibody stabilization buffer
Immunoglobulin	IgG
Form	Affinity Purified
Clonality	Polyclonal
Determinant	N-epitope
Storage	-20⁰C for long term storage
Application Protocol
DB	1:10,000
ELISA	1:10,000
Immunohistochemistry	1:50-1:150
Immunoprecipitation	1:150
Western Blot	1:500
Flowcytometry	1:100
Protein
Uniprot #	Q7RTN6
Overview	Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.
Molecular Function	ATP Binding, protein kinase activator activity, kinase binding, transferase activity, transferring phosphorus-containing groups
Subcellular Location	Nucleus, cytoplasm
Expression	Expressed in liver
Structure	Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. Contains 1 protein kinase domain.
Alternative Nomenclature	Protein kinase LYK5 antibody Serologically defined breast cancer antigen NY BR 96 antibody STE20 related adapter protein antibody STRAD alpha antibody STRAD antibody

Protein information supplied by UniProt