General Information
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Product
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LYK5 Antibody
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Description
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Affinity Purified STE20-related kinase adapter protein alpha Antibody C-epitope
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Monkey
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Immunogen
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Synthetic peptide taken within amino acid region 381-431 on human STE-20 related kinase adapter protein alpha.
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Accession #
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NCBI: NP_001003787.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.64-0.72 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Determinant
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C-epitope
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunoprecipitation |
1:150 |
Western Blot
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1:500
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Protein
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Uniprot #
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Q7RTN6
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Overview
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Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.
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Molecular Function
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ATP Binding, protein kinase activator activity, kinase binding, transferase activity, transferring phosphorus-containing groups
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Subcellular Location
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Nucleus, cytoplasm
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Expression
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Expressed in liver
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Structure
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Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Contains 1 protein kinase domain.
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Alternative Nomenclature
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Protein kinase LYK5 antibody
Serologically defined breast cancer antigen NY BR 96 antibody
STE20 related adapter protein antibody
STRAD alpha antibody
STRAD antibody
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