Synaptophysin Antibody

Product no.: SYN-101AP

$320.00

Description
Publications

General Information
Product	Synaptophysin Antibody
Description	Affinity Purified Synaptophysin Antibody N-epitope
Verified Applications	CM, ELISA, ICC, IF, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Chicken, Human, Monkey, Mouse, Rat
Immunogen	Synthetic peptide taken within amino acid region 1-100 on human Synaptophysin protein.
Specificity	This antibody does not with cross-react other synaptic vesicle proteins such as synaptotagmin, GAP45, and SNAP25 proteins.
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.60-0.62 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Determinant	N-epitope
Storage	-20⁰C for long term storage
Application Protocol
Confocal Microscopy	1:100
DOT Blot	1:10,000
ELISA	1:10,000
Immunocytochemistry	1:100
Immunofluorescence	1:100
Immunohistochemistry	1:100
Immunoprecipitation	1:125
Western Blot	1:1,000
Protein
Uniprot #	P08247
Overview	Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity.
Molecular Function	Cholesterol binding, protein self-association, transporter activity
Subcellular Location	Cytoplasmic vesicle › secretory vesicle › synaptic vesicle membrane; Multi-pass membrane protein. Cell junction ›synapse › synaptosome
Expression	Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.
Structure	Homohexamer or homotetramer. Interacts with SRCIN1.
Alternative Nomenclature	Major synaptic vesicle protein P38 antibody MRXSYP antibody Syn p38 antibody Synaptophysin antibody SYP antibody SYPH antibody SypI antibody

Protein information supplied by UniProt