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General Information
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Product
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TLR1 Antibody
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Description
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Affinity Purified Toll-like receptor 1 Antibody
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Mouse, Rat
Predicted: Human
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Immunogen
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Synthetic peptide taken within amino acid region 200-250 on mouse toll-like receptor 1 protein.
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Accession #
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NCBI: NP_109607.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.55-0.67 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:20,000
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Immunocytochemistry
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1:100
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Immunofluorescence
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1:100
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Immunohistochemistry
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1:100
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Immunoprecipitation
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1:200
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Western Blot
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1:500
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Protein
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Uniprot #
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Q9EPQ1
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Overview
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Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides.
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Molecular Function
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Receptor, Transmembrane signaling receptor activity, triacyl lipopeptide binding
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Subcellular Location
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Cell membrane; Single-pass type I membrane protein, Cytoplasmic vesicle > phagosome membrane; Single-pass type I membrane protein
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Structure
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Binds MYD88 (via TIR domains) (By similarity). Interacts (via extracellular domain) with TLR2. Ligand binding induces the formation of a heterodimer with TLR2 (By similarity). Interacts with CNPY3.
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Alternative Nomenclature
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CD281 antibody
KIAA0012 antibody
LPRS5 antibody
rsc786 antibody
Similar to Drosophila Toll protein antibody
TIL antibody
TIL. LPRS5 antibody
Tlr1 antibody
Toll (Drosophila) homolog antibody
Toll like receptor 1 antibody
Toll/Interleukin 1 receptor like antibody
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TLR1 Antibody FITC
TLR1 Antibody BIOTIN
TLR1 Blocking Peptide
TLR1 Positive Control
