TLR1 Antibody

Product no.: TLR-112AP

$285.00

Description

General Information
Product	TLR1 Antibody
Description	Affinity Purified Toll-like receptor 1 Antibody
Verified Applications	ELISA, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Predicted: Mouse, Rat
Immunogen	Synthetic peptide taken within amino acid region 370-420 on human Toll-like receptor 1.
Accession #	GenBank: AAI09094.1
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.55-0.67 µg/µl in antibody stabilization buffer
Immunoglobulin	IgG
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
ELISA	1:20,000
Immunocytochemistry	1:100
Immunofluorescence	1:100
Immunohistochemistry	1:100
Immunoprecipitation	1:200
Western Blot	1:500
Protein
Uniprot #	Q15399
Overview	Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides.
Molecular Function	Receptor, Transmembrane signaling receptor activity, triacyl lipopeptide binding
Subcellular Location	Cell membrane; Single-pass type I membrane protein, Cytoplasmic vesicle > phagosome membrane; Single-pass type I membrane protein
Structure	Binds MYD88 (via TIR domains) (By similarity). Interacts (via extracellular domain) with TLR2. Ligand binding induces the formation of a heterodimer with TLR2 (By similarity). Interacts with CNPY3.
Alternative Nomenclature	CD281 antibody CD281 antigen antibody KIAA0012 antibody LPRS5 antibody rsc786 antibody Similar to Drosophila Toll protein antibody TIL antibody TIL. LPRS5 antibody Tlr1 antibody Toll (Drosophila) homolog antibody Toll like receptor 1 antibody Toll like receptor 1 Precursor antibody Toll/Interleukin 1 receptor like antibody Toll/interleukin-1 receptor-like protein antibody

Protein information supplied by UniProt