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General Information
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Product
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TLR12 Antibody Affinity Purified
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Description
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Affinity Purified Toll-like receptor 12 Antibody
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Verified Applications
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ELISA, WB
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Host
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Rabbit
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Species Cross Reactivity
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Chimpanzee, Human, Monkey
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Immunogen
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Synthetic peptide taken within amino acid region 440-470 from mouse TLR12 protein.
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Accession #
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NCBI: NP_991392.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.55-0.69 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:20,000
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ELISA
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1:20,000
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Western Blot
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1:500
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Protein
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Uniprot #
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Q6QNU9
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Overview
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Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).
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Molecular Function
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Receptor
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Subcellular Location
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Membrane; Single-pass type I membrane protein
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Expression
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Macrophages, liver, kidney and bladder epithelial cells.
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Structure
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Binds MYD88 via their respective TIR domains.
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Alternative Nomenclature
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Toll-like receptor 12
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TLR12 Antibody FITC
TLR12 Antibody BIOTIN
TLR12 Blocking Peptide
TLR12 Positive Control
