General Information
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Product
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TOMM7 Antibody
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Description
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Affinity Purified Mitochondrial import receptor subunit TOM7 homolog Antibody
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Bovine, Human, Pig, Monkey, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 1-50 on human Mitochondrial import receptor subunit TOM7 homolog protein.
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Accession #
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NCBI: NP_061932.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.55-0.75 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Immunoprecipitation
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1:150
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Western Blot
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1:500
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Protein
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Uniprot #
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Q9P0U1
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Overview
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Required for assembly and stability of the TOM complex. Positive regulator of PARK2 translocation to damaged mitochondria. Acts probably by stabilizing PINK1 on the outer membrane of depolarized mitochondria.
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Molecular Function
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Cellular protein metabolic process; Protein targeting to mitochondrion
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Subcellular Location
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Membrane, Mitochondrion, Mitochondrion outer membrane
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Structure
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Forms part of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) which consists of at least 7 different proteins (TOMM5, TOMM6, TOMM7, TOMM20, TOMM22, TOMM40 and TOMM70).
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Alternative Nomenclature
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Mitochondrial import receptor subunit TOM7 homolog antibody
TOM7 antibody
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