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General Information
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Product
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TRAF6 Antibody Affinity Purified
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Description
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Affinity Purified TNF receptor-associated factor 6 Antibody
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Verified Applications
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ELISA, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human
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Immunogen
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Synthetic peptide corresponding to unique amino acid sequence on TRAF6 protein.
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Accession #
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NCBI: NP_665802.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.64-0.72 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Western Blot
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1:500
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Protein
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Uniprot #
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Q9Y4K3
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Overview
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Mediates synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, may be essential for formation of functional osteoclasts, seems to also play a role in dendritic cells maturation and/or activation.
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Molecular Function
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histone deacetylase binding, ligase activity, zinc ion binding, protein kindase B binding, protein N-terminus binding signal transducer activity
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Subcellular Location
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Cytoplasm, cell cortex, nucleus, lipid droplet. (Note: Found in nuclei of some aggressive B-cell lymphoma cell lines as well as in the nuclei of both resting and activated T- and B-lymphocytes. Found in punctate nuclear body protein complexes. Ubiquitinat
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Expression
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Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
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Alternative Nomenclature
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E3 ubiquitin-protein ligase TRAF6 antibody
Interleukin 1 signal transducer antibody
RING finger protein 85 antibody
RNF85 antibody
TNF receptor-associated factor 6, E3 ubiquitin protein ligase antibody
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TRAF6 Antibody FITC
TRAF6 Antibody BIOTIN
TRAF6 Blocking Peptide
TRAF6 Positive Control
