YME1L1 Antibody

General Information

Product

YME1L1 Antibody

Description

Affinity Purified ATP-dependent metalloprotease YME1L1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 720-773 on human ATP-dependent metalloprotease YME1L1 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q96TA2

Overview

Putative ATP-dependent protease which plays a role in mitochondrial protein metabolism. Ensures cell proliferation, maintains normal cristae morphology and complex I respiration activity, promotes antiapoptotic activity and protects mitochondria from the accumulation of oxidatively damaged membrane proteins. Requires to control the accumulation of nonassembled respiratory chain subunits (NDUFB6, OX4 and ND1). Seems to act in the processing of OPA1.

Molecular Function

Hydrolase, Metalloprotease, Protease

Subcellular Location

Mitochondrion inner membrane

Expression

High expression in cardiac and skeletal muscle mitochondria.

Structure

In the N-terminal section; belongs to the AAA ATPase family.

In the C-terminal section; belongs to the peptidase M41 family.

Alternative Nomenclature

ATP dependent metalloprotease FtsH1 homolog antibody

ATP-dependent zinc metalloprotease YME1L1 antibody

FTSH1 antibody

Meg-4 antibody

MEG4 antibody

PAMP antibody

Presenilin-associated metalloprotease antibody

UNQ1868/PRO4304 antibody

YME1 like 1 antibody

YME1-like protein 1 antibody

YME1L antibody