YME1L1 Antibody

Product no.: YME1L1-101AP

$285.00

Description

General Information
Product	YME1L1 Antibody
Description	Affinity Purified ATP-dependent metalloprotease YME1L1 Antibody
Verified Applications	ELISA, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide taken within amino acid region 720-773 on human ATP-dependent metalloprotease YME1L1 protein.
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.5 µg/µl in antibody stabilization buffer
Immunoglobulin	IgG
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
ELISA	1:10,000
Immunocytochemistry	1:100
Immunohistochemistry	1:100
Immunoprecipitation	1:200
Western Blot	1:500
Protein
Uniprot #	Q96TA2
Overview	Putative ATP-dependent protease which plays a role in mitochondrial protein metabolism. Ensures cell proliferation, maintains normal cristae morphology and complex I respiration activity, promotes antiapoptotic activity and protects mitochondria from the accumulation of oxidatively damaged membrane proteins. Requires to control the accumulation of nonassembled respiratory chain subunits (NDUFB6, OX4 and ND1). Seems to act in the processing of OPA1.
Molecular Function	Hydrolase, Metalloprotease, Protease
Subcellular Location	Mitochondrion inner membrane
Expression	High expression in cardiac and skeletal muscle mitochondria.
Structure	In the N-terminal section; belongs to the AAA ATPase family. In the C-terminal section; belongs to the peptidase M41 family.
Alternative Nomenclature	ATP dependent metalloprotease FtsH1 homolog antibody ATP-dependent zinc metalloprotease YME1L1 antibody FTSH1 antibody Meg-4 antibody MEG4 antibody PAMP antibody Presenilin-associated metalloprotease antibody UNQ1868/PRO4304 antibody YME1 like 1 antibody YME1-like protein 1 antibody YME1L antibody

Protein information supplied by UniProt