iNOS Antibody


iNOS Antibody

Product no.: iNOS-101AP
$295.00
$265.00


General Information

 

 

Product

 

iNOS Antibody

Description

Affinity Purified Nitric oxide synthase, inducible Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 100-150 on human inducible nitric oxide synthase protein.

Specificity

This antibody will detect both iNOS and iNOS2 protein.

Accession #

GenBank: BAA37123.1


Physical Properties

 

 

Quantity

 

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20C for long term storage


Application Protocol

 

ELISA

 

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500


Protein

 

Uniprot #

 

P35228

Overview

Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.

Molecular Function

Arginine binding, FMN binding, iron ion binding, NADPH-hemoprotein reductase activity, nitric-oxide synthase activity, receptor binding, heme binding, NADP binding

Subcellular Location

cortical cytoskeleton; cytoplasm; cytosol; intracellular; nucleus; perinuclear region of cytoplasm; peroxisome

Expression

Expressed in the liver, retina, bone cells and airway epithelial cells of the lung. Not expressed in the platelets.

Structure

Belongs to the NOS family.

Contains 1 FAD-binding FR-type domain.

Contains 1 flavodoxin-like domain.

Alternative Nomenclature

HEP NOS 

Hepatocyte NOS 

Inducible nitric oxide synthase

Inducible NO synthase 

INOS

MAC NOS 

Macrophage NOS 

Nitric oxide synthase 2 inducible macrophage 

Nitric oxide synthase 

NOS 2 

NOS 

NOS2A 

NOS2A, Inducible, Hepatocyte 

Peptidyl-cysteine S-nitrosylase NOS2 

   

Protein information supplied by UniProt
 

 

Accessories

Product Note Status Price
iNOS Antibody BIOTIN iNOS Antibody BIOTIN
iNOS-BIOTIN $350.00 *
iNOS Antibody FITC iNOS Antibody FITC
iNOS-FITC $350.00 *
iNOS Blocking Peptide iNOS Blocking Peptide
P-iNOS $145.00 *
iNOS Positive Control iNOS Positive Control
PC-iNOS $185.00 *
Display accessory details

We also recommend

iNOS2-112AP
iNOS Antibody
$265.00 *

Browse these categories as well: Nitric Oxide, Hypoxia, Metabolism, Primaries