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General Information
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Product
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FPR1 Antibody
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Description
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Affinity Purified N-formyl peptide receptor Antibody
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Verified Applications
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ELISA, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Monkey, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 150-200 on N-formyl peptide receptor.
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Accession #
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GenBank: AAA16863.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.5 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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Affinity Purified
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:10,000
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| Immunohistochemistry |
1:100 |
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Immunoprecipitation
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1:200
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Western Blot
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1:500
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Protein
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Uniprot #
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P21462
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Overview
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High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors (PubMed:2161213, PubMed:2176894, PubMed:10514456, PubMed:15153520). Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release (PubMed:2161213, PubMed:1712023, PubMed:15153520). This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system (PubMed:1712023, PubMed:10514456).
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Molecular Function
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N-formyl peptide receptor activity; Receptor activity
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Subcellular Location
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Cell membrane; Multi-pass membrane
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Structure
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Belongs to the G-protein coupled receptor 1 family.
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Alternative Nomenclature
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fMet Leu Phe receptor antibody
FMLP antibody
FMLPR antibody
Formyl peptide receptor 1 antibody
FPR 1 antibody
FPR receptor antibody
N formyl peptide chemoattractant receptor antibody
N formyl peptide receptor antibody
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FPR1 Antibody BIOTIN
FPR1 Antibody FITC
FPR1 Blocking Peptide
FPR1 Positive Control
