General Information

Product

Histone H3 Antibody

Description

Affinity Purified Histone H3 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, S. cerevisiae

Immunogen

Synthetic peptide taken within amino acid 1-50 on Sacchoromyces cerevisiae protein HH3 protein.

Accession #

Gen Bank: EDZ69636.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

B5VR08

Overview

Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. Can bind to DNA (in vitro).

Molecular Function

Chromatin regulator, Methyltransferase, Transferase

Subcellular Location

Nucleus

Structure

Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.

Contains 1 DOT1 domain.

Alternative Nomenclature

H3 histone family, member J antibody

H3 histone antibody

H3 histone family, member A antibody

H3 histone family, member B antibody

H3 histone family, member C antibody

H3 histone family, member D antibody

H3 histone family, member F antibody

H3 histone family, member H antibody

H3 histone family, member I antibody

H3 histone family, member K antibody

H3 histone family, member L antibody

H3 histone, family 3A antibody

H3.3A antibody

H3F1K antibody

H3F3 antibody

Histone cluster 1, H3a antibody

Histone cluster 1, H3b antibody

Histone cluster 1, H3c antibody

Histone cluster 1, H3d antibody

Histone cluster 1, H3e antibody

Histone cluster 1, H3f antibody

Histone cluster 1, H3g antibody

Histone cluster 1, H3i antibody

Histone cluster 1, H3j antibody

General Information

Product

SHQ1 Antibody Affinity Purified

Description

Affinity Purified Shq1p Antibody

Verified Applications

ELISA, IMM, WB

Host

Rabbit

Species Cross Reactivity

S. cerevisiae

Immunogen

Synthetic peptide taken within amino acid region 40-90 on S. cerevisiae protein.

Accession #

GenBank: AJR51992.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

P40486

Overview

Involved in the early biogenesis steps of box H/ACA snoRNP assembly.

Molecular Function

Unfolded protein binding; Box H/ACA snoRNP assembly

Subcellular Location

Nucleus

Structure

Interacts with CBF5, NAF1 and NHP2. The interaction with NAF1 and SHQ1 does not occur when NAF1 is associated with the chromatin. Contains 1 CS domain; Belongs to the SHQ1 family

Alternative Nomenclature

FLJ10539 antibody

Protein SHQ1 homolog antibody

shq1 antibody

SHQ1 homolog (S. cerevisiae) antibody

SHQ1 homolog antibody

SHQ1, H/ACA ribonucleoprotein assembly factor antibody

Shq1p antibody

General Information

Product

GPCR GPR3 Antibody Affinity Purified

Description

Affinity Purified GPR3 protein Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 5-50 on rat GPCR3 protein.

Accession #

GenBank: CAD20634.1 

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:20,000-1:50,000

ELISA

1:20,000-1:50,000

Western Blot

1:500-1:750

Protein

Uniprot #

Q8K1Q3

Overview

Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP

Molecular Function

G-protein coupled receptor, Receptor, Transducer

Subcellular Location

Cell membrane, Membrane

Expression

Abundantly expressed in granule neurons at all development stages

Structure

Belongs to the G-protein coupled receptor 1 family.

Alternative Nomenclature

ACCA antibody

ACCA orphan receptor antibody

Adenylate cyclase constitutive activator antibody

G protein coupled receptor 3 antibody

Gpr3 antibody

Probable G protein coupled receptor GPR3 antibody

General Information

Product

HIF-1-Alpha isoform 1 Antibody

Description

Affinity Purified Hypoxia-inducible factor 1-alpha isoform 1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 790-826 on human HIF1A protein.

Accession #

NCBI:  NP_001521.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.57 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q16665

Overview

Functions as a master transcriptional regulator of the adaptive response to hypoxia.

Molecular Function

Activator

Subcellular Location

Cytoplasm, Nucleus

Expression

highest levels in kidney and heart;common human cancers and their metastases, due to the presence of intratumoral hypoxia

Structure

Heterodimer

Alternative Nomenclature

ARNT interacting protein antibody

Basic-helix-loop-helix-PAS protein MOP1 antibody

bHLHe78 antibody

Class E basic helix-loop-helix protein 78 antibody

HIF 1A antibody

HIF 1alpha antibody

Hypoxia inducible factor 1 alpha antibody

Member of PAS protein 1 antibody

Member of PAS superfamily 1 antibody

MOP1 antibody

PAS domain-containing protein 8 antibody

PASD8 antibody

General Information

Product

HIF-1-Alpha isoform 1 + 2 Antibody

Description

Affinity Purified Hypoxia-inducible factor 1-alpha isoform 2 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken wtihin amino acid region 150-250 on human HIF1A protein.

Accession #

NCBI:  NP_851397.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.57 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q16665

Overview

Functions as a master transcriptional regulator of the adaptive response to hypoxia.

Molecular Function

Activator

Subcellular Location

Cytoplasm, Nucleus

Expression

highest levels in kidney and heart;common human cancers and their metastases, due to the presence of intratumoral hypoxia

Structure

Heterodimer

Alternative Nomenclature

ARNT interacting protein antibody

Basic-helix-loop-helix-PAS protein MOP1 antibody

bHLHe78 antibody

Class E basic helix-loop-helix protein 78 antibody

HIF 1A antibody

HIF 1alpha antibody

Hypoxia inducible factor 1 alpha antibody

Member of PAS protein 1 antibody

Member of PAS superfamily 1 antibody

MOP1 antibody

PAS domain-containing protein 8 antibody

PASD8 antibody

General Information

Product

ITCH / AIP4 Antibody

Description

Affinity Purified ITCH protein Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 250-300 human ITCH protein.

Accession #

GenBank: AAH11571.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.66 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q96J02

Overview

Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It catalyzes 'Lys-29'-, 'Lys-48'- and 'Lys-63'-linked ubiquitin conjugation. It is involved in the control of inflammatory signaling pathways.

Subcellular Location

Cell membrane, cytoplasm, nucleus (Note: Associates with endocytic vesicles. May be recruited to exosomes by NDFIP1)

Expression

Widely expressed

Alternative Nomenclature

AIF4 antibody

AIP4 antibody

Atrophin 1 interacting protein 4 antibody

dJ468O1.1 antibody

E3 ubiquitin-protein ligase Itchy homolog antibody

EC 6.3.2 antibody

Itch antibody

Itchy E3 ubiquitin protein ligase antibody

NAPP1 antibody

NFE2 associated polypeptide 1 antibody

Ubiquitin protein ligase ITCH antibody

General Information

Product

KIF13A Antibody

Description

Affinity Purified Kinesin-like protein KIF13A Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1700-1800 on human KIF13A isoform a protein.

Accession #

NCBI:  NP_071396.4

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.52 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q9H1H9

Overview

Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating various processes such as mannose-6-phosphate receptor (M6PR) transport to the plasma membrane, endosomal sorting during melanosome biogenesis and cytokinesis.

Molecular Function

Motor protein

Subcellular Location

Cytoplasm, Cytoskeleton, Endosome, Golgi apparatus, Membrane, Microtubule

Expression

highest levels in heart, brain and skeletal muscle

Structure

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

Alternative Nomenclature

bA500C11.2 antibody

FLJ27232 antibody

Homolog of mouse KIF13A mannose 6 phosphate receptor transporter antibody

KIF 13A antibody

Kinesin family member 13A antibody

Kinesin like protein KIF13A antibody

Kinesin like protein RBKIN antibody

RBKIN antibody

General Information

Product

Lyn Antibody

Description

Affinity Purified Tyrosine-protein kinase Lyn Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Immunogen

Synthetic peptide taken within amino acid region 425-525 on human Lyn protein.

Accession #

NCBI:  NP_002341

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P07948

Overview

Non-receptor tyrosine-protein kinase that plays role in regulation of innate and adaptive immune responses, hematopoiesis, responses to growth factors and cytokines, integrin signaling, but also responses to DNA damage and genotoxic agents

Molecular Function

Kinase, Transferase, Tyrosine-protein kinase

Subcellular Location

Cell membrane, Cytoplasm, Golgi apparatus, Membrane, Nucleus

Expression

monocytes,placenta,fetal brain, lung, liver,kidney and epidermoid, hematopoietic, and neuronal cells,also primary neuroblastoma tumors

Structure

Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily

Alternative Nomenclature

AA407514 antibody

EC 2.7.10.2 antibody

FLJ26625 antibody

Hck 2 antibody

JTK 8 antibody

Lck/Yes related novel protein tyrosine kinase antibody

LYN antibody

ONCOGENE LYN antibody

p53Lyn antibody

p56Lyn antibody

Tyrosine protein kinase LYN antibody

V yes 1 Yamaguchi sarcoma viral related oncogene homolog antibody

General Information

Product

Nogo Antibody

Description

Affinity Purified Reticulon-4 isoform A Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1100-1200 on Nogo AS protein.

Accession #

NCBI:  NP_065393.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.59-0.63 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9NQC3

Overview

Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching.  Regulates neurite fasciculation, branching and extension in the developing nervous system.

Molecular Function

poly(A) RNA binding

Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein

Expression

Isoform 1 is specifically expressed in brain and testis and weakly in heart and skeletal muscle.   Isoform 2 is widely expressed except for the liver.  Isoform 3 is expressed in brain, skeletal muscle and adipocytes.  Isoform 4 is testis-specific.

Structure

Binds to RTN4R, interacts with Bcl-xl and Bcl-2.  Isoform 2 binds to NGBR and RTN3.  Isoform 2 and Isoform 3 interact with BACE1 and BACE2, interacts with RTN4IP1 and ATL1.

Alternative Nomenclature

1110020G17Rik antibody

AA407876 antibody

AA409940 antibody

AA960376 antibody

ASY antibody

C130026I10Rik antibody

Foocen antibody

Glut4 vesicle 20 kDa protein antibody

Human NogoA antibody

Kiaa0886 antibody

KIAA4153 antibody

MGC116054 antibody

MGC139261 antibody

mKIAA0886 antibody

mKIAA4153 antibody

My043 protein antibody

Nbla00271 antibody

Nbla10545 antibody

Neurite growth inhibitor 220 antibody

Neuroendocrine-specific protein antibody

NI-250 antibody

Nogo A antibody

NOGO antibody

Nogo B antibody

Nogo C antibody

NSP antibody

NSP CL antibody

rat N antibody

Reticulon 4 antibody

Reticulon 5 antibody

RTN X antibody

RTN4 A antibody

RTN4-B1 antibody

Vp20 antibody

General Information

Product

nmt55 / NONO / p54nrb Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 430-471 on human NonO protein.

Accession #

GenBank: CAG33042.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q15233

Overview

DNA- and RNA binding protein, involved in several nuclear processes

Molecular Function

Activator, Repressor

Subcellular Location

Nucleus

Expression

Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Also found in a number of breast tumor cell lines.

Structure

Monomer and component of the SFPQ-NONO complex

Alternative Nomenclature

52 kDa subunit antibody

54 kDa nuclear RNA and DNA binding protein antibody

DNA-binding p52/p100 complex antibody

NMT 55 antibody

Non Pou domain containing octamer (ATGCAAAT) binding protein antibody

Nono antibody

NRB 54 antibody

P54 antibody

p54nrb antibody