General Information
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Product
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LILRB3 Peptide
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Description
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Antigenic Blocking Peptide Leukocyte immunoglobulin-like receptor subfamily B member 3 precursor Antibody
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic peptide taken within amino acid region 800-841 on mouse LILRB3 protein.
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Accession #
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NCBI: NP_035225.2
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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1:500
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Protein
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Uniprot #
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P97484
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Overview
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May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).
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Subcellular Location
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Cell membrane, single-pass type I membrane protein
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Expression
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Detected in macrophages, splenocytes and B lymphocytes (at protein level). Detected in macrophages, mast cells, splenocytes, peritoneal cells and natural killer cells.
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Alternative Nomenclature
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CD85 antigen like family member A antibody
HL9 antibody
IL T5 antibody
Immunoglobulin like transcript 5 antibody
LIR 3 antibody
MGC138403 antibody
Monocyte inhibitory receptor HL9 antibody
PIRB antibody
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