General Information |
|
Product |
TLR1 Peptide |
Description |
Antigenic Blocking Peptide Toll-like receptor 1 |
Verified Applications |
Immunocompeition, Immunodepletion |
Peptide Description |
Synthetic peptide taken within amino acid region 200-250 on mouse toll-like receptor 1 protein. |
Accession # |
NCBI: NP_109607.1 |
|
|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Storage |
-20⁰C for long term storage |
|
|
Competition/Depletion assay |
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|
|
Uniprot # |
|
Overview |
Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. |
Molecular Function |
Receptor, Transmembrane signaling receptor activity, triacyl lipopeptide binding |
Subcellular Location |
Cell membrane; Single-pass type I membrane protein, Cytoplasmic vesicle > phagosome membrane; Single-pass type I membrane protein |
Structure |
Binds MYD88 (via TIR domains). Interacts (via extracellular domain) with TLR2. Ligand binding induces the formation of a heterodimer with TLR2. Interacts with CNPY3. |
Alternative Nomenclature |
CD281 antibody KIAA0012 antibody LPRS5 antibody rsc786 antibody Similar to Drosophila Toll protein antibody TIL antibody TIL. LPRS5 antibody Tlr1 antibody Toll (Drosophila) homolog antibody Toll like receptor 1 antibody Toll/Interleukin 1 receptor like antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
TLR-101AP | |||
|
TLR1-FITC | |||
|
TLR1-BIOTIN | |||
|
PC-TLR1 | |||
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