General Information |
|
Product |
PREX1 Peptide |
Description |
Antigenic Blocking Peptide Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein |
Verified Applications |
Immunodepletion, Immunocompetition |
Peptide Description |
Synthetic peptide corresponding to aino acid region 815-836 of Human PREX1. Peptide was covalently modified.
Sequence: QEEDQADSAFPLLSLGPRLSLC |
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|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Storage |
-20⁰C for long term storage |
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|
Competition/Depletion assay |
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Uniprot # |
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Overview |
Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils. |
Molecular Function |
enzyme binding, Rho GTPase activator activity, Rho guanyl-nucleotide exchange factor activity, phospholipid binding |
Subcellular Location |
Cytoplasm, cell membrane |
Expression |
Mainly expressed in peripheral blood leukocytes and brain. Expressed at intermediate level in spleen and lymph nodes, and weakly expressed in other tissues. |
Alternative Nomenclature |
4 antibody 5)-dependent Rac exchanger 1 antibody P REX1 antibody PtdIns(3,4,5) dependent Rac exchanger 1 antibody SET domain containing 6 antibody Setd6 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
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PREX-101AP | |||
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PREX-FITC | |||
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PREX-BIOTIN | |||
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PC-PREX1 | |||
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