General Information |
|
Product |
PREX1 Positive Control |
Description |
Western Blot Positive Control Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein |
Verified Applications |
WB |
Immunogen |
Purified Protein |
|
|
Quantity |
5 Applications |
Volume |
Inquire |
Form |
Western Blot Positive Control |
Storage |
-20⁰C for long term storage |
|
|
Western Blot |
1:500-1:750 |
|
|
Uniprot # |
|
Overview |
Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils. |
Molecular Function |
enzyme binding, Rho GTPase activator activity, Rho guanyl-nucleotide exchange factor activity, phospholipid binding |
Subcellular Location |
Cytoplasm, cell membrane |
Expression |
Mainly expressed in peripheral blood leukocytes and brain. Expressed at intermediate level in spleen and lymph nodes, and weakly expressed in other tissues. |
Alternative Nomenclature |
4 antibody 5)-dependent Rac exchanger 1 antibody P REX1 antibody PtdIns(3,4,5) dependent Rac exchanger 1 antibody SET domain containing 6 antibody Setd6 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
PREX-101AP | |||
|
PREX-FITC | |||
|
P-PREX | |||
|
PREX-BIOTIN | |||
Display accessory details |
Select your currency:
(c) FabGennix International Inc.