General Information

Product

ADCY5 Antibody

Description

Affinity Purified Adenylyl cyclase type 5 mRNA Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Rat, Mouse

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on rat Particulate Adenylyl Cyclase 5 protein.

Accession #

GenBank: M96159.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200-1:1,000

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200-1:1,000

Immunofluorescence

1:200-1:1,000

Immunohistochemistry

1:200-1:1,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q04400

Overview

Membrane bound calcium-inhibitable adenylyl cyclase.

Molecular Function

Adenylate cyclase activity; cAMP biosynthesis; ATP-binding; Magnesium; Metal binding; Nucleotide-binding

Subcellular Location

Membrane; Multi-pass membrane protein; Cell projection; cilium

Structure

Part of a complex containing AKAP5, ADCY6, PDE4C and PKD2.  Interacts with RAF1.

Alternative Nomenclature

AC 5 antibody

Adcy5 antibody

Adenylate cyclase type V antibody

Adenylyl cyclase 5 antibody

ATP pyrophosphate-lyase 5 antibody

General Information

Product

ADCY8 Antibody

Description

Affinity Purified Particulate adenylate cyclase 8 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on human Particulate Adenylyl Cyclase 8 protein.

Accession #

GenBank:  AAZ13596.1

Quantity

100 µg

Volume

200 µl

Concentration

0.6 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q4F7X0

Overview

Involved in intracellular signal transduction and adenylate cyclase activity.

Molecular Function

Adenylate cyclase activity; cAMP biosynthesis; ATP-binding; Magnesium; Metal binding; Nucleotide-binding

Subcellular Location

Integral component of membrane

Structure

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Alternative Nomenclature

ADCY3 antibody

ATP pyrophosphate-lyase 8 antibody

Brain adenylate cyclase 8 antibody

Ca(2+)/calmodulin activated adenylyl cyclase antibody

HBAC1 antibody

General Information

Product

Bone marrow stromal cell antigen 1 Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to amino acids 255-274 of Human Bone marrow stromal cell antigen 1. Peptide was covalently modified.

Sequence:

FQY SCI NDY RPV KLL QCV DH 

Accession #

GenBank: AAH12095

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Western Blot

1:500

Protein

Uniprot #

Q10588

Overview

Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth.

Molecular Function

Hydrolase, Transferase

Subcellular Location

Cell Membrane

Expression

Widely Expressed

Structure

Homodimer

Alternative Nomenclature

ADP ribosyl cyclase 2 antibody

Bone marrow stromal antigen 1 antibody

BST 1 antibody

cADPr hydrolase 2 antibody

CD157 antibody

Cyclic ADP ribose hydrolase 2 antibody

NAD(+) nucleosidase antibody

General Information

Product

Annexin A10 Antibody

Description

Affinity Purified annexin A10 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Rat

Immunogen

Synthetic peptide taken within amino acid region 60-100 on human Annexin A10 protein.

Accession #

NCBI:  NP_009124

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DOT Blot

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9UJ72

Overview

Caclium-dependent phospholipid binding and calcium ion binding

Subcellular Location

Mitochondrion

Structure

Contains 4 annexin repeats; belongs to annexin family.

Alternative Nomenclature

annexin 14 antibody

ANX 14 antibody

ANXA 10 antibody

General Information

Product

Annexin A1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-50 on human annexin A1 protein.

Accession #

NCBI:  NP_000691

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P04083

Overview

Calcium/phospholipid-binding protein that promotes membrane fusion and is invovled in excocytosis.  Regulates phospholipase A2 activity.

Molecular Function

Phospholipase A2 inhibitor

Subcellular Location

Nucleus; Cytoplasm; Cell projection, cilium; Basolateral cell membrane

Expression

Detected in resting neutrophils. Detected in peripheral blood T-cells. Detected in extracellular vesicles in blood serum from patients with inflammatory bowel disease, but not in serum from healthy donors. Detected in placenta. Detected in liver.

Structure

Homodimer in placenta; linked by transgultamylation.

Alternative Nomenclature

ANX 1 antibody

ANX A1 antibody

Calpactin 2 antibody

Chromobindin 9 antibody

Lipocortin 1 antibody

LPC1 antibody

p35 antibody

Phospholipase A2 inhibitory protein antibody

General Information

Product

Annexin A6 Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 500-560 on human Annexin A6 protein.

Accession #

GenBank: AAH17046

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P08133

Overview

Regulates release of calcium ions from intracellular stores.  Associated with CD21

Molecular Function

Calcium and phospholipid-binding

Subcellular Location

Cytoplasm; Melanosome

Expression

Induced by Epstein-Barr virus

Structure

Pair of annexin repeats may form one binding site for calcium and phospholipid.  Contains 8 annexin repeats.

Alternative Nomenclature

67 kDa calelectrin antibody

ANX 6 antibody

Calcium binding protein p68 antibody

Calphobindin II antibody

CBP68 antibody

Chromobindin 20 antibody

p68 antibody

P70 antibody

Protein III antibody

General Information

Product

Calcium Sensing Receptor Antibody

Description

Affinity Purified extracellular calcium-sensing receptor Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Predicted: Rabbit, Horse, Chicken, Cow, Dog, Chimpanzee, Macaque Monkey

Immunogen

Synthetic peptide corresponding to amino acids 47-69 on human CASR gene.

Sequence:

KDQDLKSRPESVECIRYNFRGFR

Accession #

NCBI: NP_000379.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.7 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500. Predicted molecular weight: 121 kDa

Protein

Uniprot #

P41180

Overview

Senses change in extracellular concentration of calcium channels.

Molecular Function

GPCR, Receptor, Transducer.

Subcellular Location

Cell membrane; Mulipass membrane protein.

Expression

Temporal lobe, frontal lobe, parietal lobe, hippocampus, cerebellum, kidney, lung, liver, heart, skeletal muscle and placenta.

Structure

Interacts with VCP, RNF19A and ARRB1.

Alternative Nomenclature

CAR antibody

EIG8 antibody

FHH antibody

FIH antibody

GPRC2A antibody

HHC1 antibody

Hypocalciuric hypercalcemia 1 severe neonatal hyperparathyroidism antibody

NSHPT antibody

Parathyroid Cell calcium-sensing receptor antibody

PCAR1 antibody

General Information

Product

CAB39 Antibody

Description

Calcium Binding Protein 39 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on human CAB39 protein.

Accession #

NCBI:  BC010652.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.72 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9Y376

Overview

Component of a complex that binds and activates STK11/LKB1.

Molecular Function

Kinase binding, protein kinase activator activity, protein serine/threonine kinase activator activity

Subcellular Location

Cytoplasm

Structure

Component of trimeric complex composed of STK11/LKB1, STRAD, and CAB39.  Tethers STK11/LKB! In the cytoplasm and stimulates its catalytics activity.

Alternative Nomenclature

CGI 66 antibody

MO25 alpha antibody

General Information

Product

CHERP Antibody

Description

Affinity Purified SR-related CTD associated factor 6 Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Predicted: Horse, Guinea pig, Cow, Cat, Dog, Zebrafish

Immunogen

Synthetic peptide corresponding to a region within internal seuence amino acids 846-913 of human CHERP.

Sequence:

EQGIQDPIKG GDVRDKWDQY  KGVGVALDDP YENYRRNKSY SFIARMKARD

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.7 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500. Predicted Molecular weight: 104 kDa

Protein

Uniprot #

Q8IWX8

Overview

Involved in calcium homeostasis growth and proliferation

Molecular Function

RNA processing; cellular calcium ion homeostasis

Subcellular Location

Cytoplasm; Endoplasmic Reticulum

Expression

Brain, placenta, lung, liver, kidney, pancreas, cardiac and skeletal muscle and in cultured HEL and Dami cells.

Structure

Contains 1 CID domain, 1 G-patch domain and 1 SURP motif repeat

Alternative Nomenclature

Calcium homeostasis endoplasmic reticulum protein antibody

DAN16 antibody

DAN26 antibody

Protein with polyglutamine repeat antibody

SCAF6 antibody

SR related CTD associated factor 6 antibody

SRA1 antibody

General Information

Product

EFEMP1 Antibody

Description

Affinity Purified EGF-containing fibulin-like extracellular matrix protein 1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic cyclic peptide corresponding to N terminal amino acids 25-42 of Human EFEMP1, peptide was covalently modified.

Sequence:

TYTQCTDGYEWDPVRQQC

Accession #

NCBI: XP_005264262.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500. Predicted molecular weight 60 kDa

Protein

Uniprot #

UPI000387D485

Overview

Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth.

Molecular Function

Calcium

Subcellular Location

Secreted; Extracellular space

Expression

In the eye, associated with photoreceptor outer and inner segment regions, the nerve fiber layer, outer nuclear layer and inner and outer plexiform layers of the retina.

Structure

Interacts with ECM1. Interacts with TIMP3.

Alternative Nomenclature

DHRD antibody

Doyne honeycomb retinal degeneration antibody

DRAD antibody

EFEMP 1 antibody

Epidermal growth factor containing fibulin like extracellular matrix protein 1 antibody

FBLN3 antibody

Fibrillin like antibody

FIBULIN 3 antibody

FLJ35535 antibody

Heat shock 70 KD protein 1 antibody

MGC111353 antibody

MLVT antibody

T16 protein antibody