General Information

Product

TLR11 Antibody Affinity Purified

Description

Affinity Purified Toll-like receptor 11 precursor Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Chimpanzee, Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 430-460 on human TLR11 protein.

Accession #

NCBI:  NP_991388.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.56-0.72 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:20,000

ELISA

1:20,000

Western Blot

1:500

Protein

Uniprot #

Q6R5P0

Overview

Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).

Molecular Function

Receptor, transmembrane signaling receptor activity

Subcellular Location

Membrane; Single-pass type I membrane protein

Structure

Binds MYD88 via their respective TIR domains (By similarity). Interacts with HSP90B1; this interaction is required for proper folding in the endoplasmic reticulum.

Alternative Nomenclature

hgnc31753 antibody

Toll like receptor 11 antibody

General Information

Product

TLR10 Antibody

Description

Affinity Purified Toll-like receptor 10 Antibody

Verified Applications

ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Chimpanzee, Human, Monkey, Pig, Rat

Immunogen

Synthetic peptide taken within amino acid region 380-430 on human TLR10 protein.

Accession #

GenBank: AAQ88667.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.67 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:20,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q9BXR5

Overview

Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).

Molecular Function

Receptor, transmembrane signaling receptor activity

Subcellular Location

Membrane; Single-pass type I membrane protein

Expression

Highly expressed in spleen, lymph node, thymus, tonsil and at lower levels in lung. Highly expressed in promyelocytic HL-60 cells and in B-cell lines.

Structure

Binds MYD88 via their respective TIR domains (By similarity). Homodimer (Potential).

Alternative Nomenclature

CD 290 antibody

CD 290 antigen antibody

TLR10 antibody

Toll like receptor 10 antibody

UNQ315/PRO358 antibody

General Information

Product

Themis Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse

Immunogen

Synthetic peptide taken within amino acid region 1-50 on Thymocyte-expressed molecule involved in selection protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.72 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q8N1K5

Overview

Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells.

Molecular Function

Developmental protein

Subcellular Location

Cytoplasm, nucleus

Alternative Nomenclature

C6orf190 antibody

C6orf207 antibody

MGC163388 antibody

Protein THEMIS antibody

SIGNALING PHOSPHOPROTEIN SPECIFIC FOR T CELLS antibody

SPOT antibody

THEMIS antibody

Thymocyte expressed molecule involved in selection antibody

Thymocyte selection pathway associated antibody

TSEPA antibody

General Information

Product

ACTH Antibody

Description

Affinity Purified Adrenocorticotropin Hormone Antibody

Verified Applications

ELISA, IHC-Fr, IHC-P, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Predicted: Chicken, Chimpanzee, Cow, Dog, Goat, Guinea pig, Macaque Monkey, Orangutan, Sheep

Immunogen

Synthetic peptide corresponding to ACTH aa 138-176. 

Sequence:

SYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEF

Accession #

NCBI:  AAX36901

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.67-0.68 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:250

Immunocytochemistry

1:250

Immunofluorescence

1:200

Immunohistochemistry

1:250

Immunoprecipitation

1:200

Western Blot

1:1000 Predicted Molecular weight: 29 kDa

Protein

Uniprot #

UPI00004EBE53

Overview

Stimulates adrenal glands and release cortisol.

Molecular Function

GPCR; Hormone activity

Subcellular Location

Secreted

Expression

ACTH and MSH are produced by the pituitary gland

Structure

Belongs to POMC family

Alternative Nomenclature

Alpha Melanocyte Stimulating Hormone antibody

Beta Endorphin antibody

Beta Lipotropin antibody

Beta Melanocyte Stimulating Hormone antibody

Beta-endorphin antibody

CLIP antibody

Corticotropin Like Intermediary Peptide antibody

Met-enkephalin antibody

MSH antibody

NPP antibody

Opiomelanocortin prepropeptide antibody

POC antibody

POMC antibody

Tetracosactide antibody

General Information

Product

Alpha 1 Fetoprotein Antibody

Description

Affinity Purified alpha-fetoprotein Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Rat

Immunogen

Full length native protein (purified) corresponding to Human alpha 1 Fetoprotein. Purified human alpha 1 Fetoprotein.

Accession #

GenBank: AAB58754.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P02771

Overview

Binds copper, nickel, fatty acids, bilirubin.

Molecular Function

Copper, Nickel; metal-binding

Subcellular Location

Secreted

Expression

Plasma. Synthesized by fetal liver and yolk sac.

Structure

Dimeric and trimeric forms have been found in addition to the monomeric form

Alternative Nomenclature

AFP antibody

Alpha fetoglobulin antibody

Alpha fetoprotein antibody

Alpha-1-fetoprotein antibody

Alpha-fetoglobulin antibody

Alpha-fetoprotein antibody

alpha-fetoprotein, Hereditary persistence of, included antibody

FETA antibody

Hereditary persistence of alpha fetoprotein antibody

HPAFP antibody

General Information

Product

Bovine Lactoferrin Antibody

Description

Affinity Purified Lactoferrin Antibody

Verified Applications

CM, ELISA, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Sheep

Immunogen

Purified bovine Lactoferrin protein

Accession #

GenBank:  ACT76166

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.75 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

D3G9G3

Overview

Ferric iron binding; iron ion homeostasis and transport

Subcellular Location

Extracellular region

Structure

Belongs to transferrin family

Alternative Nomenclature

CKRX antibody

GIG12 antibody

Growth inhibiting protein 12 antibody

HLF2 antibody

Homo sapiens chemokine receptor X antibody

Kaliocin 1 antibody

LF antibody

LTF antibody

Neutrophil lactoferrin antibody

Talalactoferrin alfa antibody

General Information

Product

Bone marrow stromal cell antigen 1 Antibody

Verified Applications

CM, ELISA, ICC, IF, IHC, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to amino acids 255-274 of Human Bone marrow stromal cell antigen 1. Peptide was covalently modified.

Sequence:

FQY SCI NDY RPV KLL QCV DH 

Accession #

GenBank: AAH12095

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Western Blot

1:500

Protein

Uniprot #

Q10588

Overview

Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth.

Molecular Function

Hydrolase, Transferase

Subcellular Location

Cell Membrane

Expression

Widely Expressed

Structure

Homodimer

Alternative Nomenclature

ADP ribosyl cyclase 2 antibody

Bone marrow stromal antigen 1 antibody

BST 1 antibody

cADPr hydrolase 2 antibody

CD157 antibody

Cyclic ADP ribose hydrolase 2 antibody

NAD(+) nucleosidase antibody

General Information

Product

CCR4 Antibody

Description

Affinity Purified C-C chemokine receptor type 4 Antibody

Verified Applications

CF, DB, ELISA, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Cat, Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-50 on human C-C chemokine receptor type 4 protein.

Accession #

NCBI: NP_005499

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.68 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:250

Immunocytochemistry

1:250

Immunofluorescence

1:250

Immunohistochemistry

1:250

Immunoprecipitation

1:250

Western Blot

1:500

Protein

Uniprot #

P51679

Overview

Receptor for C-C type chemokines CCL17/TARC and CCL22/MDC.  Functions as chemoattractant homing receptor on circulating memory lymphocytes and as coreceptor for some primary HIV-2 isolates.  Can also mediate hippocampal-neuron survival.

Molecular Function

GPCR, Receptor, Transducer.

Subcellular Location

Cell membrane; Multi-pass membrane protein

Expression

Thymus, peripheral blood leukocytes including T-cells, CD4+ cells, basophils and in platelets.  Expressed less in spleen and in monocytes.  Also found in macrophages, IL-2-activated natural killer cells and skin-homing memory T-cells, mostly the ones expresseding cutaneous lymphocyte antigen.  Expressed in brain and microvascular and coronary artery endothelial cells.

Structure

Belongs to G-protein coupled receptor 1 family.  Interacts with CREB3.

Alternative Nomenclature

CD194 antibody

ChemR13 antibody

CKR4 antibody

CMKBR 4 antibody

HGCN 14099 antibody

K5 5 antibody

General Information

Product

CCR7 Antibody

Description

Affinity Purified C-C chemokine receptor type 7 Antibody

Verified Applications

CM, DB, ELISA, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on CCR7 protein.

Accession #

NCBI: NP_955783

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65-1.25 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:250

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:250

Immunofluorescence

1:250

Immunohistochemistry

1:250

Western Blot

1:500

Protein

Uniprot #

Q6U2D6

Molecular Function

G-protein coupled receptor

Subcellular Location

Membrane

Structure

Belongs to G-protein coupled receptor 1 family; Transmembrane helix

Alternative Nomenclature

BLR 2 antibody

C C chemokine receptor type 7 antibody

C C CKR 7 antibody

CCR 7 antibody

CD 197 antibody

CDW197 antibody

CMKBR7 antibody

EBI 1 antibody

EBV Induced G Protein Coupled Receptor 1 antibody

Epstein Barr virus induced G protein coupled receptor antibody

EVI 1 antibody

Lymphocyte Specific G Protein Coupled Peptide Receptor antibody

MGC108519 antibody

MIP3 Beta Receptor antibody

General Information

Product

CCR2 Antibody

Description

Affinity Purified C-C chemokine receptor type 2 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 20-70 on human CCR2 protein.

Accession #

NCBI: NP_955783

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.61-0.71 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P41597

Overview

Receptor for CCL2, CCL7 and CCL13 chemokines.  Transduces a signal by increasing intracellular calcium ion levels.  Alternative coreceptor with CD4 for HIV-1 infection.

Molecular Function

Host-virus interaction; GPCR; Transducer

Subcellular Location

Cell membrane; Mulipass membrane protein.

Expression

Induced; Up-regulated by CREB3

Structure

Binds to HIV-1 Tat.  Interacts with ARRB1

Alternative Nomenclature

CC CKR 2 antibody

CD192 antibody

CKR2A antibody

CKR2B antibody

CMKBR2 antibody

MCP1 RECEPTOR antibody

Monocyte chemoattractant protein 1 receptor antibody