General Information
|
|
Product
|
Eprhin Receptor A6 Peptide
|
Description
|
Antigenic Blocking Peptide Ephrin type-A receptor 6 isoform A Antibody
|
Verified Applications
|
Immunocompetition, Immunodepletion
|
Peptide Description
|
Synthetic Peptide
|
Accession #
|
NCBI: NP_001073917
|
Physical Properties
|
|
Quantity
|
250 µg
|
Volume
|
100 µl
|
Form
|
Antigenic Blocking Peptide
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
Competition/Depletion assay
|
Refer to competition assay protocol
|
Protein
|
Uniprot #
|
B3KS12
|
Overview
|
Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity).
|
Molecular Function
|
ATP-binding, Nucleotide-binding
|
Subcellular Location
|
Membrane; Single-pass type I membrane protein
|
Expression
|
Expressed in brain and testis.
|
Structure
|
Heterotetramer upon binding of the ligand. The heterotetramer is composed of an ephrin dimer and a receptor dimer. Oligomerization is probably required to induce biological responses (By similarity).
|
Alternative Nomenclature
|
Ehk 2 antibody
EPH homology kinase 2 antibody
Eph Receptor A6 antibody
ephrin receptor EphA6 antibody
Hek12 antibody
|
|
|