General Information

Product

Olig2 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-50 on human Olig2 protein.

Accession #

GenBank:  AAH36245.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunohistochemistry

1:100

Western Blot

1:500

Protein

Uniprot #

Q13516

Overview

Necessary for oligodendrocyte and motor neuron specification in the spinal cord.  In the hindbrain it is  needed in the development of somatic neurons.

Molecular Function

Developmental protein, DNA binding

Subcellular Location

Nucleus; Cytoplasm

Expression

Is expressed in the brain in oligodendrocytes.  Is expressed strongly in oligodendrogliomas with weaker expression in astrocytomas

Structure

Interacts with NKX2-3

Alternative Nomenclature

Basic domain helix loop helix protein class B 1 antibody

BHLHB antibody

bHLHB1 antibody

bHLHe19 antibody

Class B basic helix loop helix protein 1 antibody

class E basic helix loop helix protein 19 antibody

Human protein kinase C binding protein RACK17 antibody

Olig2 antibody

Oligo2 antibody

Oligodendrocyte lineage transcription factor 2 antibody

Oligodendrocyte specific bHLH transcription factor 2 antibody

PRKCBP2 antibody

Protein kinase C binding protein 2 antibody

Protein kinase C binding protein RACK17 antibody

RACK17 antibody

General Information

Product

Olig2 Antibody

Description

Affinity Purified OLIG2 protein Antibody C-epitope

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to Human Olig2 amino acids 136-156. The selected peptide was post-synthetically modified to achieve highest antigenicity before coupling to a carrier protein using hetero-bifunctional cross linker for immunogen preparation.

Sequence:

PYAHGPSVRKLSKIATLLLAR

Accession #

GenBank:  AAH36245.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DOT Blot

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

Q13516

Overview

Necessary for oligodendrocyte and motor neuron specification in the spinal cord.  In the hindbrain it is  needed in the development of somatic neurons.

Molecular Function

Developmental protein, DNA binding

Subcellular Location

Nucleus; Cytoplasm

Expression

Is expressed in the brain in oligodendrocytes.  Is expressed strongly in oligodendrogliomas with weaker expression in astrocytomas

Structure

Interacts with NKX2-3

Alternative Nomenclature

Basic domain helix loop helix protein class B 1 antibody

BHLHB antibody

bHLHB1 antibody

bHLHe19 antibody

Class B basic helix loop helix protein 1 antibody

class E basic helix loop helix protein 19 antibody

Human protein kinase C binding protein RACK17 antibody

Olig2 antibody

Oligo2 antibody

Oligodendrocyte lineage transcription factor 2 antibody

Oligodendrocyte specific bHLH transcription factor 2 antibody

PRKCBP2 antibody

Protein kinase C binding protein 2 antibody

Protein kinase C binding protein RACK17 antibody

RACK17 antibody

General Information

Product

Noelin Antibody Affinity Purified

Description

Affinity Purified Noelin isoform a precursor Antibody C-epitope

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Mouse

Immunogen

C-epitope synthetic peptide taken within amino acid region 130-230 on Noelin-1 protein.

Accession #

NCBI: NP_062371.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.72 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q8R357

Molecular Function

beta-amyloid binding

Subcellular Location

extracellular space

Alternative Nomenclature

AMY antibody

NEUROBLASTOMA PROTEIN antibody

Neuronal olfactomedin-related ER localized protein antibody

Noe1 antibody

Noelin antibody

OlfA antibody

Olfactomedin 1 antibody

Olfm1 antibody

Pancortin 1 antibody

General Information

Product

Noelin Antibody Affinity Purified

Description

Affinity Purified Noelin isoform a precursor Antibody N-epitope

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Mouse

Immunogen

N-epitope synthetic peptide taken within amino acid region 1-60 on Noelin-1 protein.

Accession #

NCBI: NP_062371.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.72 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q8R357

Molecular Function

beta-amyloid binding

Subcellular Location

extracellular space

Alternative Nomenclature

AMY antibody

NEUROBLASTOMA PROTEIN antibody

Neuronal olfactomedin-related ER localized protein antibody

Noe1 antibody

Noelin antibody

OlfA antibody

Olfactomedin 1 antibody

Olfm1 antibody

Pancortin antibody

General Information

Product

S100 beta Antibody Affinity Purified

Description

Affinity Purified Protein S100-P Antibody N-epitope

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Rat

Immunogen

N-epitope synthetic peptide corresponding to unique amino acid sequences on human S100 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P25815

Overview

May function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE).

Molecular Function

Calcium-dependent protein binding, calcium ion binding, magnesium ion binding

Subcellular Location

Nucleus, cytoplasm, Cell projection > microvillus membrane

Expression

Detected in all of the tissues except brain, testis and small intestine, expression level is higher in placenta, heart, lung, skeletal muscle, spleen and leukocyte. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial n

Structure

Homodimer and heterodimer with S100A1. Interacts with S100PBP and S100Z. Interacts with CACYBP in a calcium-dependent manner. Dimeric form binds to and activates EZR/Ezrin by unmasking its F-actin binding sites. Interacts with PPP5C (via TPR repeats); the

Alternative Nomenclature

NEF antibody

S 100 calcium binding protein beta chain antibody

S 100 protein beta chain antibody

S 100 protein beta subunit antibody

S100 calcium-binding protein B antibody

General Information

Product

S100 beta Antibody Affinity Purified

Description

Affinity Purified Protein S100-P Antibody C-epitope

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Rat

Immunogen

C-epitope synthetic peptide corresponding to unique amino acid sequences on human S100 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P25815

Overview

May function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE).

Molecular Function

Calcium-dependent protein binding, calcium ion binding, magnesium ion binding

Subcellular Location

Nucleus, cytoplasm, Cell projection > microvillus membrane

Expression

Detected in all of the tissues except brain, testis and small intestine, expression level is higher in placenta, heart, lung, skeletal muscle, spleen and leukocyte. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial n

Structure

Homodimer and heterodimer with S100A1. Interacts with S100PBP and S100Z. Interacts with CACYBP in a calcium-dependent manner. Dimeric form binds to and activates EZR/Ezrin by unmasking its F-actin binding sites. Interacts with PPP5C (via TPR repeats); the

Alternative Nomenclature

NEF antibody

S 100 calcium binding protein beta chain antibody

S 100 protein beta chain antibody

S 100 protein beta subunit antibody

S100 calcium-binding protein B antibody

General Information

Product

S100 beta Antibody

Verified Applications

CM, ELISA, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse

Immunogen

Full length protein of human S100 beta/beta homodimer.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

P25815

Overview

May function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE).

Molecular Function

Calcium-dependent protein binding, calcium ion binding, magnesium ion binding

Subcellular Location

Nucleus, cytoplasm, Cell projection > microvillus membrane

Expression

Detected in all of the tissues except brain, testis and small intestine, expression level is higher in placenta, heart, lung, skeletal muscle, spleen and leukocyte. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias.

Structure

Homodimer and heterodimer with S100A1. Interacts with S100PBP and S100Z. Interacts with CACYBP in a calcium-dependent manner. Dimeric form binds to and activates EZR/Ezrin by unmasking its F-actin binding sites. Interacts with PPP5C (via TPR repeats); the interaction is calcium-dependent and modulates PPP5C activity.

Alternative Nomenclature

NEF antibody

S 100 calcium binding protein beta chain antibody

S 100 protein beta chain antibody

S 100 protein beta subunit antibody

S100 calcium-binding protein B antibody

General Information

Product

Pax2 Antibody

Description

Affinity Purified Pan Paired box protein Pax-2 Antibody Mid-region

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 255-305 on human PAX2 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

Mid-region

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q02962

Overview

Probable transcription factor that may have a role in kidney cell differentiation. Has a critical role in the development of the urogenital tract, the eyes, and the CNS.

Molecular Function

Developmental protein, core promoter proximal region sequence-specific DNA binding, DNA binding

Subcellular Location

Nucleus

Expression

Expressed in primitive cells of the kidney, ureter, eye, ear and central nervous system.

Structure

Mainly in fetal kidney and juvenile nephrogenic rests.

Alternative Nomenclature

Paired box 2 antibody

Paired box gene 2 antibody

paired box protein 2 antibody

Paired box protein Pax 2 antibody

Pax 2 antibody

General Information

Product

IFITM3 Antibody

Description

Affinity Purified Interferon-induced transmembrane protein 3 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Monkey

Immunogen

Synthetic peptide taken within amino acid region 1-50 on human Interferon-induced transmembrane protein 3.

Accession #

GenBank: AFF60350

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

Q01628

Overview

IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV) and Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Plays a critical role in the structural stability and function of vacuolar ATPase (v-ATPase). Establishes physical contact with the v-ATPase of endosomes which is critical for proper clathrin localization and is also required for the function of the v-ATPase to lower the pH in phagocytic endosomes thus establishing an antiviral state.

Molecular Function

Antiviral defense, Immunity, Innate immunity

Subcellular Location

Cell membrane; Single-pass type II membrane protein

Late endosome membrane; Single-pass type II membrane protein

Lysosome membrane; Single-pass type II membrane protein

Expression

Induced by IFN-alpha and IFNG/IFN-gamma.

Structure

Interacts with ATP6V0B and CD81. Interacts with SPP1; the interaction reduces OPN expression. Interacts with VAPA.

Alternative Nomenclature

1 8U 

Fragilis 

IFITM3 

Interferon Induced Transmembrane Protein 3

Interferon inducible 

Interferon inducible protein 1 8U 

Interferon Inducible Protein 15 

Interferon Inducible Protein Homolog 

IP15 

General Information

Product

Pax2 Antibody

Description

Affinity Purified Pan Paired box protein Pax-2 Antibody Mid-region

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 255-305 on human PAX2 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Determinant

Mid-region

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:250-1:500

Protein

Uniprot #

Q02962

Overview

Probable transcription factor that may have a role in kidney cell differentiation. Has a critical role in the development of the urogenital tract, the eyes, and the CNS.

Molecular Function

Developmental protein, core promoter proximal region sequence-specific DNA binding, DNA binding

Subcellular Location

Nucleus

Expression

Expressed in primitive cells of the kidney, ureter, eye, ear and central nervous system.

Structure

Mainly in fetal kidney and juvenile nephrogenic rests.

Alternative Nomenclature

Paired box 2 antibody

Paired box gene 2 antibody

paired box protein 2 antibody

Paired box protein Pax 2 antibody

Pax 2 antibody