General Information |
|
Product |
PDE3A Peptide |
Description |
Antigenic Blocking Peptide cGMP-inhibited 3',5'-cyclic phosphodiesterase A isoform 1 |
Verified Applications |
Immunodepletion, Immunocompetition |
Peptide Description |
Synthetic peptide selective only for PDE3A variants. |
Accession # |
NCBI: NP_000912.3 |
|
|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Storage |
-20⁰C for long term storage |
|
|
Competition/Depletion assay |
|
|
|
Uniprot # |
|
Overview |
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. |
Molecular Function |
Hydrolase, 3', 5'-cyclic-GAP phosphodiesterase activity, cAMP binding |
Subcellular Location |
Membrane; Multi-pass membrane protein |
Alternative Nomenclature |
cAMP phosphodiesterase myocardial cGMP inhibited antibody CGI PDE A antibody CGI PDE antibody Cyclic GMP-inhibited phosphodiesterase A antibody Human cGMP inhibited cAMP phosphodiesterase mRNA antibody PDE 3A antibody Phosphodiesterase 3A antibody Phosphodiesterase 3A cGMP inhibited antibody |
Protein information supplied by UniProt
FabGennix PDE3A Antibody has been used in 23 Publications |
|
Yang, Zhaokang, et al. "The Golgi apparatus is a functionally distinct Ca2+ store regulated by the PKA and Epac branches of the β1-adrenergic signaling pathway." Sci. Signal. 8.398 (2015): ra101-ra101. PMID26462734
|
Western Blot; Rat |
Fields, Laura A., Andreas Koschinski, and Manuela Zaccolo. "Sustained exposure to catecholamines affects cAMP/PKA compartmentalised signalling in adult rat ventricular myocytes." Cellular signalling (2015). PMID26475678
|
Confocal imaging, FRET, Western Blot; Rat |
Rajagopal, Senthilkumar, et al. "Cytokine-Induced S-Nitrosylation of Soluble Guanylyl Cyclase and Expression of Phosphodiesterase 1A Contribute to Dysfunction of Longitudinal Smooth Muscle Relaxation." Journal of Pharmacology and Experimental Therapeutics 352.3 (2015): 509-518. PMID25550199
|
Western Blot; Mouse |
Petersen, T. S., et al. "Distribution and function of 3', 5'-Cyclic-AMP phosphodiesterases in the human ovary." Molecular and cellular endocrinology (2015). PMID25578602
|
Immunocytochemistry; Human |
Mahavadi, Sunila, et al. "Cytokine-induced iNOS and ERK1/2 inhibit adenylyl cyclase type 5/6 activity and stimulate phosphodiesterase 4D5 activity in intestinal longitudinal smooth muscle." American Journal of Physiology-Cell Physiology 307.4 (2014): C402-C411.PMID24944202
|
Western Blot; Mouse |
Amanda, G. Vang, et al. "Regulatory T-cells and cAMP suppress effector T-cells independently of PKA-CREM/ICER: a potential role for Epac." Biochemical Journal 456.3 (2013): 463-473. PMID24007532
|
Western Blot; Mouse |
MacDougall, David A. et al. “Caveolae Compartmentalise Β2-Adrenoceptor Signals by Curtailing cAMP Production and Maintaining Phosphatase Activity in the Sarcoplasmic Reticulum of the Adult Ventricular Myocyte.”Journal of Molecular and Cellular Cardiology 52.2 (2012): 388–400. PMC3270222
|
Western Blot; Rat |
Ückert, Stefan, et al. "Expression and distribution of phosphodiesterase isoenzymes in the Human seminal vesicles." The journal of sexual medicine 8.11 (2011): 3058-3065. PMID21810184
|
Immunohistochemistry, Western Blot; Human |
Nishioka, Kinue, et al. "Cilostazol Suppresses Angiotensin II–Induced Vasoconstriction via Protein Kinase A–Mediated Phosphorylation of the Transient Receptor Potential Canonical 6 Channel." Arteriosclerosis, thrombosis, and vascular biology 31.10 (2011): 2278-2286. PMID21799177
|
Western Blot; Rat |
Schmidt, Eric P. et al. “Soluble Guanylyl Cyclase Contributes to Ventilator-Induced Lung Injury in Mice.” American Journal of Physiology - Lung Cellular and Molecular Physiology 295.6 (2008): L1056–L1065. PMC2604795
|
Western Blot; Mouse |
We could not fit all of our publications on this page!
For a complete listing of FabGennix PDE3A publications, please click here.
Publishing research using PD3A-101AP? Please let us know, we can cite the reference in this datasheet.
Product | Note | Status | Price | |
---|---|---|---|---|
|
PD3A-101AP | |||
|
PD3A-FITC | |||
|
PD3A-BIOTIN | |||
|
PC-PD3A | |||
Display accessory details |
Select your currency:
(c) FabGennix International Inc.