General Information |
|
Product |
PDE6 Beta Antibody FITC |
Description |
FITC-Conjugated Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta Antibody |
Verified Applications |
ELISA, CM, ICC, IF, IHC, WB |
Host |
Rabbit |
Species Cross Reactivity |
Bovine, Human, Mouse, Pig, Rat |
Immunogen |
Synthetic cyclic petide common to all PDE6 Beta variants |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.5 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
Confocal Microscopy |
1:200 |
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunocytochemistry |
1:200 |
Immunofluorescence |
1:200 |
Immunohistochemistry |
1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
This protein participates in processes of transmission and amplification of the visual signal. Necessary for the formation of a functional phosphodiesterase holoenzyme. |
Molecular Function |
Hydrolase, 3', 5' -cyclic-AMP phosphodiesterase activity |
Subcellular Location |
Membrane; lipid anchor |
Structure |
Oligomer composed of two catalytic chains (alpha and beta), an inhibitory chain (gamma) and the delta chain. |
Alternative Nomenclature |
5''-cyclic phosphodiesterase subunit beta antibody Congenital stationary night blindness 3 autosomal dominant antibody CSNB 3 antibody CSNBAD2 antibody DPDE 4 antibody GMP-PDE beta antibody PDE 6 beta antibody PDE 6B antibody PDEB antibody Phosphodiesterase 6B antibody Rd 1 antibody Rod cGMP specific 3' 5' cyclic phosphodiesterase beta subunit antibody Rod cGMP-specific 3'' antibody RP40 antibody |
Protein information supplied by UniProt
Fabgennix PDE6 Beta Antibody has been used in 2 Publication |
|
Nikolova, Sevdalina et al. “Phosphodiesterase 6 Subunits Are Expressed and Altered in Idiopathic Pulmonary Fibrosis.” Respiratory Research 11.1 (2010): 146. PMC2988012
|
Immunohistochemistry, Western Blot; Human, Pig |
Nikolova, Sevdalina Vaskova. Role of cGMP phosphodiesterases in idiopathic pulmonary fibrosis. Diss. Justus Liebig University Giessen, 2009. PMID20979602
|
Immunohistochemistry, Western Blot; Human |
Publishing research using PD6-201AP? Please let us know, we can cite the reference in this datasheet.
Product | Note | Status | Price | |
---|---|---|---|---|
|
PD6-201AP | |||
|
P-PD6B | |||
|
PD6B-BIOTIN | |||
|
PC-PD6B | |||
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