General Information
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Product
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DWORF Peptide
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Description
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Antigenic Blocking Peptide Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF Antibody
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synththetic peptide corresponding to full length Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF protein.
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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P0DN83
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Overview
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Enhances the activity of ATP2A1/SERCA1 ATPase in sarcoplasmic reticulum by displacing ATP2A1/SERCA1 inhibitors, thereby acting as a key regulator of skeletal muscle activity. Does not directly stimulates SERCA pump activity. Enhances sarcoplasmic reticulum Ca2+ uptake and myocyte contractility by displacing the SERCA inhibitory peptides sarcolipin (SLN), phospholamban (PLN) and myoregulin (MRLN).
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Molecular Function
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Sarcoplasmic reticulum membrane; Single-pass membrane protein
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Alternative Nomenclature
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Dwarf open reading frame antibody,DWORF antibody,Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORFSERCA regulator DWORF antibody,
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