General Information
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Product
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ENT1 Peptide
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Description
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Antigenic Blocking Peptide Equilibrative nitrobenzylthioinosine-sensitive nucleoside transporter ENT1
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic peptide taken within amino acid reigon 410-460 on mouse Equilibrative nitrobenzylthioinosine-sensitive nucleoside transporter ENT1 protein.
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Accession #
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GenBank: AAF64035.2
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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Q9JIM1
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Overview
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Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Resistant to dipyridamole and dilazep inhibition (anticancer chemotherapeutics drugs).
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Molecular Function
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Nucleoside transmembrane transporter activity
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Subcellular Location
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Cell membrane; Basolateral cell membrane; Apical cell membrane
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Expression
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Highly expressed in heart, spleen, lung, liver and testis. Lower level of expression in brain and kidney.
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Structure
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Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
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Alternative Nomenclature
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Equilibrative NBMPR-sensitive nucleoside transporter antibody
Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter antibody
Equilibrative nucleoside transporter 1 antibody
es-type antibody
Nucleoside transporter, es-type antibody
Slc29a1 antibody
solute carrier family 29 (equilibrative nucleoside transporter), member 1 antibody
Solute carrier family 29 member 1 antibody
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