General Information |
|
Product |
Apelin Receptor Antibody BIOTIN |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 330-377 rat Apelin receptor protein. |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.5 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
BIOTIN-Conjugated |
Purification Method |
Immobilized antigen affinity chromatography |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
ELISA |
1:50,000 |
Immunohistochemistry | 1:50-1:150 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure, heart contractility, and heart failure. Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for APELA hormone. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia. |
Molecular Function |
Developmental protein, G-protein coupled receptor, Receptor, Transducer |
Subcellular Location |
Cell membrane, Multi-pass membrane protein |
Expression |
Widely expressed in the brain, in glial cells, astrocytes and neuronal subpopulations, as well as in the spleen, thymus, ovary, small intestine and colon. |
Structure |
Transmembrane, Transmembrane helix |
Alternative Nomenclature |
AGTRL1 ligand antibody APEL antibody Apelin-13 antibody APJ endogenous ligand antibody Apln antibody XNPEP2 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
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APLNR-101AP | |||
|
APLNR-FITC | |||
|
P-APLNR | |||
|
PC-APLNR | |||
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