General Information |
|
Product |
Phospho-Cofilin Antibody FITC |
Description |
FITC-Conjugated Phosphorylated Cofilin Antibody |
Verified Applications |
ELISA, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Mouse, Rat |
Immunogen |
Synthetic peptide corresponding to amino acids within region 1-50 on human Phosphorylated Cofilin. |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.5-1.5 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
FITC-Conjugated |
Purification Method |
Immobilized antigen affinity chromatography |
Clonality |
Polyclonal |
Modification |
Phosphorylated |
Storage |
-20?C for long term storage |
|
|
ELISA |
1:50,000 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500-1:5,000 |
|
|
Uniprot # |
|
Overview |
Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity (PubMed:11812157). In conjunction with the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions via regulation of actin dynamics (PubMed:15580268). Required for the centralization of the mitotic spindle and symmetric division of zygotes (By similarity). |
Molecular Function |
actin filament binding |
Subcellular Location |
Plasma membrane, Cytoskeleton, Nucleus |
Expression |
Widely distributed in various tissues. |
Structure |
Belongs to the actin-binding proteins ADF family. |
Alternative Nomenclature |
18 kDa phosphoprotein antibody CFL 1 antibody CFL antibody CFL1 antibody COF1_HUMAN antibody Cofilin 1 antibody Cofilin 1 non muscle antibody Cofilin antibody Cofilin non muscle isoform antibody Cofilin-1 antibody epididymis secretory protein Li 15 antibody HEL-S-15 antibody non-muscle isoform antibody p18 antibody |
Protein information supplied by UniProt.
Product | Note | Status | Price | |
---|---|---|---|---|
|
PCFL-140AP | |||
|
PCFL-BIOTIN | |||
|
P-PCFL | |||
|
PC-PCFL | |||
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