General Information |
|
Product |
ITCH / AIP4 Positive Control |
Verified Applications |
WB |
Immunogen |
Purified Protein |
Accession # |
GenBank: AAH11571.1 |
|
|
Quantity |
5 Applications |
Volume |
Inquire |
Form |
Western Blot Positive Control |
Storage |
-20⁰C for long term storage |
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|
Western Blot |
1:500 |
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|
Uniprot # |
|
Overview |
Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It catalyzes 'Lys-29'-, 'Lys-48'- and 'Lys-63'-linked ubiquitin conjugation. It is involved in the control of inflammatory signaling pathways. |
Subcellular Location |
Cell membrane, cytoplasm, nucleus (Note: Associates with endocytic vesicles. May be recruited to exosomes by NDFIP1) |
Expression |
Widely expressed |
Alternative Nomenclature |
AIF4 antibody AIP4 antibody Atrophin 1 interacting protein 4 antibody dJ468O1.1 antibody E3 ubiquitin-protein ligase Itchy homolog antibody EC 6.3.2 antibody Itch antibody Itchy E3 ubiquitin protein ligase antibody NAPP1 antibody NFE2 associated polypeptide 1 antibody Ubiquitin protein ligase ITCH antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
ITCH-101AP | |||
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ITCH-FITC | |||
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P-ITCH | |||
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ITCH-BIOTIN | |||
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