General Information |
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Product |
ABL2 Positive Control |
Description |
Western Blot Positive Control Tyrosine-protein kinase ABL2 Antibody |
Verified Applications |
WB |
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Quantity |
5 Applications |
Volume |
Inquire |
Concentration |
The concentration of the sample is empirically set so that 20 µl per lane in Western and blotted with corresponding affinity purified antibody will give a clean band with a high signal to noise ratio on the gel. |
Form |
Western Blot Positive Control |
Storage |
-20?C for long term storage |
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Uniprot # |
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Overview |
Non-receptor tyrosine-protein kinase that plays an ABL1-overlapping role in key processes linked to cell growth and survival such as cytoskeleton remodeling in response to extracellular stimuli, cell motility and adhesion and receptor endocytosis. Coordinates actin remodeling through tyrosine phosphorylation of proteins controlling cytoskeleton dynamics like MYH10 (involved in movement); CTTN (involved in signaling); or TUBA1 and TUBB (microtubule subunits). Binds directly F-actin and regulates actin cytoskeletal structure through its F-actin-bundling activity. Involved in the regulation of cell adhesion and motility through phosphorylation of key regulators of these processes such as CRK, CRKL, DOK1 or ARHGAP35. |
Molecular Function |
actin filament binding actin monomer binding ATP binding magnesium ion binding manganese ion binding non-membrane spanning protein tyrosine kinase activity phosphotyrosine residue binding protein kinase activity protein tyrosine kinase activity |
Subcellular Location |
Cytoskeleton |
Expression |
Widely expressed. |
Alternative Nomenclature |
Abelson murine leukemia viral oncogene homolog 2 antibody Abelson related gene protein antibody Abelson tyrosine-protein kinase 2 antibody Abelson-related gene protein antibody ABL2 antibody ABL2_HUMAN antibody ABLL antibody ARG antibody Tyrosine kinase ARG antibody Tyrosine protein kinase ABL2 antibody Tyrosine-protein kinase ARG antibody v abl Abelson murine leukemia viral oncogene homolog 2 antibody |
Protein information supplied by UniProt.
Product | Note | Status | Price | |
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ABL2-201AP | |||
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ABL2-BIOTIN | |||
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ABL2-FITC | |||
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P-ABL2 | |||
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