General Information
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Product
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ARTS Antibody BIOTIN-Conjugated
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Description
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BIOTIN-Conjugated Septin-4 Antibody
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Verified Applications
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ELISA, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 400-450 on SEPT4 protein.
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.68-075 µg/µl in antibody stabilization buffer
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Form
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BIOTIN-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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DB
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1:10,000
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ELISA
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1:10,000
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Western Blot
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1:500
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Protein
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Uniprot #
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O43236
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Overview
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Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion. Isoform ARTS, but not the other isoforms, is required for the induction of cell death mediated by TGF-beta and by other apoptotic stimuli.
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Molecular Function
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GTPase activity, structural molecule activity, GTP binding
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Subcellular Location
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Cytoplasm, cytoskeleton. (Note: In platelets, found in areas surrounding alpha-granules)
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Expression
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Widely expressed in adult and fetal tissues with highest expression in adult brain (at protein level), heart, liver and adrenal gland and fetal heart, kidney, liver and lung. Also expressed in colorectal cancers and malignant melanomas. Expressed in plate
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Alternative Nomenclature
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Apoptosis Related Protein TGFb Signalling antibody
ARTS antibody
Bradeion beta antibody
Brain protein H5 antibody
CE5B3 antibody
CE5B3 beta antibody
cell division control-related protein 2 antibody
cerebral protein 7 antibody
H5 antibody
hCDCREL-2 antibody
Hucep 7 antibody
MART antibody
Peanut-like protein 2 antibody
PNUTL2 antibody
SEP4 antibody
SEPT4 antibody
Septin-4 antibody
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