General Information |
|
Product |
SIRT1 Antibody FITC-Conjugated |
Description |
FITC-Conjugated NAD-dependent protein deacetylase sirtuin-1 isoform 1 Antibody |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Chicken, Human, Monkey, Mouse, Rat |
Immunogen |
Synthetic peptide taken within amino acid 25-75 on rat Sirtuin 1 protein. |
Accession # |
NCBI: NP_062786.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.69-0.75 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunohistochemsitry | 1:100 |
Immunoprecipitation | 1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in coordination of several separated cellular functions such as cell cycle, response to DNA damage, metabolism, apoptosis and autphagy. |
Subcellular Location |
Nucleus, PML body, cytoplasm. (Nucleus: Recruited to the nuclear bodies via its interaction with the PML. Colocalized with APEX1 in nucleus. May be found in nucleolus, nuclear euchromatin, heterochromatin and inner membrane. Shuttles between nucleus and cytoplasm). |
Expression |
Widely expressed. Weakly expressed in liver and skeletal muscle. |
Alternative Nomenclature |
75SirT1 antibody HST2, S. cerevisiae, homolog of antibody NAD dependent deacetylase sirtuin 1 antibody Regulatory protein SIR2 homolog 1 antibody SIR2 like protein 1 antibody SIR2, S.cerevisiae, homolog-like 1 antibody SIR2ALPHA antibody SIR2L1 antibody SirtT1 75 kDa fragment antibody Sirtuin type 1 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
SIR1-101AP | |||
|
P-SIR1 | |||
|
SIR1-BIOTIN | |||
|
PC-SIR1 | |||
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