General Information
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Product
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TGM1 Antibody
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Description
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Affinity Purified Coagulation factor XIII A chain Antibody C-epitope
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Verified Applications
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CM, ELISA, ICC, IHC, IF, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human, Mouse, Rat
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Immunogen
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Synthetic peptide corresponding to unique amino acid sequence on Coagulation factor XIIIA chain precursor
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.61-0.65 µg/µl in antibody stabilization buffer
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Form
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Affinity Purified
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Clonality
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Polyclonal
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Determinant
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C-epitope
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Storage
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-20⁰C for long term storage
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Application Protocol
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Confocal Microscopy
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1:250
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Dot Blot
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1:30,000
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ELISA
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1:30,000
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Immunocytochemistry
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1:250
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Immunofluorescence
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1:250
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Immunohistochemistry
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1:250
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Western Blot
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1:450
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Protein
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Uniprot #
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Q8BH61
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Overview
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Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
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Molecular Function
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metal ion binding, protein-glutamine gamma-glutamyltransferase activity
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Subcellular Location
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Cytoplasm, Secreted
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Structure
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Tetramer of two A chains and two B chains
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Alternative Nomenclature
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ARCI1 antibody
Epidermal TGase antibody
ICR2 antibody
KTG antibody
LI antibody
LI1 antibody
Protein glutamine gamma glutamyltransferase K antibody
TG(K) antibody
TGase 1 antibody
TGASE antibody
TGase K antibody
TGK antibody
TGM1 antibody
Transglutaminase 1 (K polypeptide epidermal type I, protein glutamine gamma glutamyltransferase) antibody
Transglutaminase 1 antibody
Transglutaminase K antibody
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