General Information

Product

Aquaporin 5 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Human, Sheep, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 250-299 on rat Aquaporin 5 protein.

Accession #

GenBank: AAH78904

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.52-0.65 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q6AYU6

Overview

Forms a water-specific channel and is osmoreceptor which regulates body water balance and mediates water flow ithin the CNS.

Molecular Function

Transport

Subcellular Location

Membrane; Multi-pass protein

Expression

Expressed predominantly in the ependymal cell lining the aqueductal system and over the space of the brain in contact with subarachnoid space.  Weakly detectable in eye, kidney, intestine and lung.

Structure

Contain two tandem repeats each with three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala

Alternative Nomenclature

AQP 5 antibody

Aquaporin 5 antibody

General Information

Product

Aquaporin 6 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Human, Sheep, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 220-270 on rat Aquaporin 6 protein.

Accession #

NCBI:  NP_071517.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.65-0.75 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:400

Protein

Uniprot #

Q9WTY0

Overview

Forms water specific channel.  Invovled in several physiological functions including glomerular filtration, tubular endocytosis, and acid-base metabolism

Molecular Function

Transport

Subcellular Location

Cytoplasmic vessicle membrane; Multi-pass membrane protein

Expression

Kidney

Structure

Contain two tandem repeats each with three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala

Alternative Nomenclature

AQP-6 antibody

AQP2L antibody

Aquaporin 2 like antibody

aquaporin 2 like kidney specific antibody

Aquaporin 6 antibody

Aquaporin 6 kidney specific antibody

hKID antibody

Human kidney water channel (hKID) mRNA, complete cds antibody

KID antibody

Kidney-specific aquaporin antibody

General Information

Product

Aquaporin 7 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Human, Sheep, Mouse, Rat

Immunogen

Synthetic amidated peptide taken within amino acid region 150-200 on rat Aquaporin 7 protein, covalently modified and conjugated to KLH.

Accession #

NCBI:  NP_062030.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.58 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500; Predicted Molecular Weight: 37 kDa

Protein

Uniprot #

O54794

Overview

Forms water and glycerol channel

Molecular Function

Transport

Subcellular Location

Membrane; Multi-pass protein

Expression

Membranes

Structure

Contain two tandem repeats each with three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala

Alternative Nomenclature

AQP 7 antibody

AQP 7L antibody

AQP 9 antibody

AQPap antibody

Aquaglyceroporin-7 antibody

Aquaporin 7 like antibody

Aquaporin adipose antibody

Aquaporin-7 antibody

MGC149555 antibody

MGC149556 antibody

General Information

Product

Aquaporin 8 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Human, Sheep, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 215-263 on rat Aquaporin 8 protein.

Accession #

GenBank: BAA21918

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50-0.95 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P56405

Overview

Forms water specific channel.  Mercury-sensitive.  Plays role in spermatogenesis, fertilization, and in secretion of pancreatic juice and saliva.

Molecular Function

Transport

Subcellular Location

Membrane; Multi-pass protein

Expression

Sperm, pancreas and liver.  Less expressed in salivary gland and absoptive colonic epithelial cells.

Structure

Contain two tandem repeats each with three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala

Alternative Nomenclature

AQP8 antibody

Aquaporin 8 antibody

General Information

Product

Aquaporin 9 Antibody

Verified Applications

ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Sheep, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 250-294 on rat Aquaporin 9 protein.

Accession #

NCBI:  NP_075249

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.8 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P56627

Overview

Forms a channel with broad specificity.  Mediates passage of wide variety of non-charged solutes.

Molecular Function

Transport

Expression

Highly expressed in peripheral leukocytes. Also expressed in liver, lung, and spleen.

Subcellular Location

Membrane; Multi-pass protein

Structure

Contain two tandem repeats each with three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala

Alternative Nomenclature

AQP 9 antibody

Aquaglyceroporin-9 antibody

Aquaporin 9 antibody

HsT 17287 antibody

Small solute channel 1 antibody

SSC 1 antibody

General Information

Product

Aquaporin 11 Antibody

Verified Applications

CM, ELISA, ICC/IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Pig, Rat

Immunogen

Synthetic peptide taken within amino acid region 140-190 on Aquaporin 11 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.57-0.67 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:50

Immunofluorescence

1:50

Immunohistochemistry

1:500

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

Q8CHM1

Overview

Transport of water and small neutral solutes across cell membranes

Molecular Function

Transport

Subcellular Location

Membrane; Multi-pass protein

Expression

Dendrite, cell surface, plasma membrane, endoplasmic reticulum

Structure

Contain two tandem repeats each with three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala

Alternative Nomenclature

AQP-11 antibody

Aquaporin-11 antibody

General Information

Product

Aquaporin 10 Antibody

Verified Applications

ELISA, ICC, IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 250-300 on human Aquaporin 10 protein.

Accession #

NCBI: XP_011508406.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.88 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunocytochemistry

1:100

Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

UPI0005D02B6D

Overview

Water cahnnel promoting glycerol permeability and water transport.  Contributes to water transport in upper portion of small intestine.

Molecular Function

Transport

Subcellular Location

Membrane; Multi-pass protein

Expression

Duodenum and jejunum.  Highest expression in absorptive epithelial cells at the tips of villi in the jejunum

Structure

Contain two tandem repeats each with three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala

Alternative Nomenclature

AQP 10 antibody

AQPA Human antibody

Aquaglyceroporin-10 antibody

Aquaporin-10 antibody

Small intestine aquaporin antibody

General Information

Product

Calcium Sensing Receptor Antibody

Description

Affinity Purified extracellular calcium-sensing receptor Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Predicted: Rabbit, Horse, Chicken, Cow, Dog, Chimpanzee, Macaque Monkey

Immunogen

Synthetic peptide corresponding to amino acids 47-69 on human CASR gene.

Sequence:

KDQDLKSRPESVECIRYNFRGFR

Accession #

NCBI: NP_000379.2

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.7 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500. Predicted molecular weight: 121 kDa

Protein

Uniprot #

P41180

Overview

Senses change in extracellular concentration of calcium channels.

Molecular Function

GPCR, Receptor, Transducer.

Subcellular Location

Cell membrane; Mulipass membrane protein.

Expression

Temporal lobe, frontal lobe, parietal lobe, hippocampus, cerebellum, kidney, lung, liver, heart, skeletal muscle and placenta.

Structure

Interacts with VCP, RNF19A and ARRB1.

Alternative Nomenclature

CAR antibody

EIG8 antibody

FHH antibody

FIH antibody

GPRC2A antibody

HHC1 antibody

Hypocalciuric hypercalcemia 1 severe neonatal hyperparathyroidism antibody

NSHPT antibody

Parathyroid Cell calcium-sensing receptor antibody

PCAR1 antibody

General Information

Product

CAB39 Antibody

Description

Calcium Binding Protein 39 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse

Immunogen

Synthetic peptide corresponding to unique amino acid sequence on human CAB39 protein.

Accession #

NCBI:  BC010652.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.64-0.72 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q9Y376

Overview

Component of a complex that binds and activates STK11/LKB1.

Molecular Function

Kinase binding, protein kinase activator activity, protein serine/threonine kinase activator activity

Subcellular Location

Cytoplasm

Structure

Component of trimeric complex composed of STK11/LKB1, STRAD, and CAB39.  Tethers STK11/LKB! In the cytoplasm and stimulates its catalytics activity.

Alternative Nomenclature

CGI 66 antibody

MO25 alpha antibody

General Information

Product

C3Orf34 Antibody

Description

Affinity Purified Chromosome 3 orf 34 Antibody

Verified Applications

DB, ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid region 120-170 on human Chromosome open reading frame 34 protein.

Accession #

NCBI: AAH07827

Physical Properties

Quantity

100 µg

Volume

200 µl

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:2,000

ELISA

1:2,000

Western Blot

1:500-1:1,000

Protein

Uniprot #

Q96LK0

Molecular Function

Cell projection, Cytoplasm, Cytoskeleton

Structure

Belongs to the CEP19 Family

Alternative Nomenclature

Chromosome 3 open reading frame 34 antibody

HSD5 antibody

LOC84984 antibody

MGC14126 antibody