General Information |
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Product |
Aurora B Positive Control |
Description |
Western Blot Positive Control Aurora Kinase B |
Verified Applications |
WB |
Accession # |
NCBI: NP_004208.2 |
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Quantity |
5 Applications |
Volume |
Inquire |
Form |
Western Blot Positive Control |
Storage |
-20⁰C for long term storage |
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Western Blot |
1:2,500-1:5,000 |
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Uniprot # |
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Overview |
Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. |
Molecular Function |
ATP binding histone serine kinase activity kinase binding metal ion binding protein serine/threonine/tyrosine kinase activity protein serine/threonine kinase activity |
Subcellular Location |
Spindle, Nucleus |
Expression |
High level expression seen in the thymus. It is also expressed in the spleen, lung, testis, colon, placenta and fetal liver. Expressed during S and G2/M phase and expression is up-regulated in cancer cells during M phase. |
Structure |
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily. |
Alternative Nomenclature |
AIK2 antibody AIM1 antibody ARK2 antibody AurB antibody AURKB antibody Aurora 1 antibody Aurora and Ipl1 like midbody associated protein 1 antibody Aurora kinase B antibody Aurora related kinase 2 antibody Aurora- and Ipl1-like midbody-associated protein 1 antibody Aurora-B antibody Aurora/IPL1 related kinase 2 antibody IPL1 antibody PPP1R48 antibody Protein phosphatase 1 regulatory subunit 48 antibody Serine/threonine-protein kinase 12 antibody Serine/threonine-protein kinase aurora-B antibody STK1 antibody STK12 antibody STK5 antibody |
Protein information supplied by UniProt.
Product | Note | Status | Price | |
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AURKB-BIOTIN | |||
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AURKB-FITC | |||
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P-AURKB | |||
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AURKB-201AP | |||
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