General Information

Product

Human Lactoferrin Antibody

Verified Applications

ELISA, ICC/IF, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Full length native protein purified human Lactoferrin.

Accession #

GeneBank: AAA59511

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.8 µg/µl in antibody stabilization buffer

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P02788

Overview

Iron binding transport proteins which bind two Fe3+ ions in association with the binding of an anion usually bicarbonate. Binds to bacterial surface and is crucial for the bactericidal functions.  Has some antiviral activity against papillomavirus infection.

Molecular Function

DNA binding, Heparin Binding, Iron, metal Binding, Immunity

Subcellular Location

Secreted; Cytoplasmic granule; Nucleus

Expression

Saliva, tears, serum, plasma, urine, distal collecting tubules in the medulla, peripheral blood leukocytes.

Structure

Belongs to transferrin family; Contains 2 transferrin-like domains

Alternative Nomenclature

CKRX antibody

GIG12 antibody

Growth inhibiting protein 12 antibody

HLF2 antibody

Homo sapiens chemokine receptor X antibody

Kaliocin 1 antibody

Lactoferrin antibody

Lactoferroxin A antibody

Lactoferroxin B antibody

Lactoferroxin-C antibody

Lactotransferrin antibody

LF antibody

LTF antibody

Neutrophil lactoferrin antibody

Talalactoferrin alfa antibody

General Information

Product

VPRBP Antibody

Description

Affinity Purified VPR Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human Immunodeficiency Virus 1

Immunogen

Synthetic peptide taken within amino acid region 1-27 on human VPR protein.

Accession #

GenBank: AGV39791.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.52 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

T2D0A6

Overview

During virus entry, involved in the transport of the viral pre-integration (PIC) complex to the nucleus (PubMed:12417576). This function is crucial for viral infection of non-dividing macrophages (PubMed:12417576). May act directly at the nuclear pore complex, by binding nucleoporins phenylalanine-glycine (FG)-repeat regions. During virus replication, may deplete host UNG protein, and incude G2-M cell cycle arrest(PubMed:7666531, PubMed:7474100). Acts by targeting specific host proteins for degradation by the 26S proteasome, through association with the cellular CUL4A-DDB1 E3 ligase complex by direct interaction with host VPRPB/DCAF-1. Cell cycle arrest reportedly occurs within hours of infection and is not blocked by antiviral agents, suggesting that it is initiated by the Vpr carried into the virion. Additionally, Vpr induces apoptosis in a cell cycle dependent manner suggesting that these two effects are mechanistically linked. Detected in the serum and cerebrospinal fluid of AIDS patient, Vpr may also induce cell death to bystander cells (PubMed:11000244).

Molecular Function

Viral Life Cycle

Subcellular Location

Virion; Host nucleus; Host Extracellular Space

Structure

Homooligomer, may form homodimer (PubMed:7798208). Interacts with p6-gag region of the Pr55 Gag precursor protein through a (Leu-X-X)4 motif near the C terminus of the P6gag protein (PubMed:7474102). Interacts with host UNG (PubMed:9151883). May interact with host RAD23A/HHR23A (PubMed:9371639). Interacts with host VPRBP/DCAF1, leading to hijack the CUL4A-RBX1-DDB1-DCAF1/VPRBP complex, mediate ubiquitination of host proteins such as TERT and ZGPAT and arrest the cell cycle in G2 phase (PubMed:17314515, PubMed:17630831, PubMed:17314515).

Alternative Nomenclature

DCAF1 antibody

DDB1 and CUL4 associated factor 1 antibody

HIV-1 Vpr-binding protein antibody

KIAA0800 antibody

protein VPRBP antibody

RIP antibody

Vpr (HIV-1) binding protein antibody

VPR BP antibody

Vpr interacting protein antibody

Vpr-binding protein antibody

General Information

Product

C6orf150 Antibody

Description

Affinity Purified Cyclic GMP-AMP synthase Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 450-500 on mouse cGAS protein.

Accession #

NCBI: NP_775562

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.60 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500

Protein

Uniprot #

Q8C6L5

Overview

Catalyzes the formation of cyclic GMP-AMP from ATP and GTP.  Has antiviral activity through acting as a cystolic DNA senser.

Molecular Function

Nucleotidyltransferase; ATP binding; DNA binding

Subcellular Location

Cytoplasm; Cytosol

Expression

Is expressed in the monocytic cell line THP1 by type 1 Interferons

Structure

Monomer when in absence of DNA.  Homodimer when bound to DNA.

Alternative Nomenclature

C6orf150 antibody

cGAMP synthase antibody

cGAS antibody

Chromosome 6 open reading frame 150 antibody

Cyclic GMP-AMP synthase antibody

h-cGAS antibody

Hypothetical protein LOC115004 antibody

Mab 21 domain containing 1 antibody

MB21D1 antibody

protein MB21D1 antibody

Uncharacterized protein C6orf150 antibody

General Information

Product

C6orf150 Antibody

Description

Affinity Purified Cyclic GMP-AMP synthase Antibody N-epitope

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid regions 350-450 on human cGAS protein.

Accession #

NCBI:  NP_612450

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.60 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q8N884

Overview

Catalyzes the formation of cyclic GMP-AMP from ATP and GTP.  Has antiviral activity through acting as a cystolic DNA senser.

Molecular Function

Nucleotidyltransferase; ATP binding; DNA binding

Subcellular Location

Cytoplasm; Cytosol

Expression

Is expressed in the monocytic cell line THP1 by type 1 Interferons

Structure

Monomer when in absence of DNA.  Homodimer when bound to DNA.

Alternative Nomenclature

C6orf150 antibody

cGAMP synthase antibody

cGAS antibody

Chromosome 6 open reading frame 150 antibody

Cyclic GMP-AMP synthase antibody

h-cGAS antibody

Hypothetical protein LOC115004 antibody

Mab 21 domain containing 1 antibody

MB21D1 antibody

protein MB21D1 antibody

Uncharacterized protein C6orf150 antibody

General Information

Product

C6orf150 Antibody

Description

Affinity Purified Cyclic GMP-AMP synthase Antibody C-epitope

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human

Immunogen

Synthetic peptide taken within amino acid regions 400-450 on human cGAS protein.

Accession #

NCBI:  NP_612450

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.60 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

Q8N884

Overview

Catalyzes the formation of cyclic GMP-AMP from ATP and GTP.  Has antiviral activity through acting as a cystolic DNA senser.

Molecular Function

Nucleotidyltransferase; ATP binding; DNA binding

Subcellular Location

Cytoplasm; Cytosol

Expression

Is expressed in the monocytic cell line THP1 by type 1 Interferons

Structure

Monomer when in absence of DNA.  Homodimer when bound to DNA.

Alternative Nomenclature

C6orf150 antibody

cGAMP synthase antibody

cGAS antibody

Chromosome 6 open reading frame 150 antibody

Cyclic GMP-AMP synthase antibody

h-cGAS antibody

Hypothetical protein LOC115004 antibody

Mab 21 domain containing 1 antibody

MB21D1 antibody

protein MB21D1 antibody

Uncharacterized protein C6orf150 antibody

General Information

Product

Hepatitis C virus Core NS3 + NS4 Antibody Affinity Purified

Description

Affinity Purified NS3-4 protein, partial Antibody C-epitope

Verified Applications

DB, ELISA, WB

Host

Rabbit

Species Cross Reactivity

Hepatitis C virus

Immunogen

C-epitope specific synthetic peptide corresponding to unique amino acid sequences on hepatitis C polyprotein.

Accession #

GenBank: BAA03177.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50-0.65 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

C-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:20,000-1:50,000

ELISA

1:20,000-1:50,000

Western Blot

1:500

Protein

Uniprot #

Q81588

Overview

ATP binding, ATP-dependent helicase activity, Viral genome replication

Subcellular Location

Virion

Alternative Nomenclature

helicase NS3 antibody

Non structural protein 4A antibody

Non structural protein 4B antibody

NS3P antibody

NS4A antibody

NS4B antibody

NTPase antibody

p27 antibody

p70 antibody

p8 antibody

Serine protease antibody

General Information

Product

Hepatitis C virus Core NS3 + NS4 Antibody Affinity Purified

Description

Affinity Purified NS3-4 protein, partial Antibody N-epitope

Verified Applications

DB, ELISA, WB

Host

Rabbit

Species Cross Reactivity

Hepatitis C virus

Immunogen

N-epitope specific synthetic peptide corresponding to unique amino acid sequences on hepatitis C polyprotein.

Accession #

GenBank: BAA03177.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.50-0.65 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Determinant

N-epitope

Storage

-20⁰C for long term storage

Application Protocol

DB

1:20,000-1:50,000

ELISA

1:20,000-1:50,000

Western Blot

1:500

Protein

Uniprot #

Q81588

Overview

ATP binding, ATP-dependent helicase activity, Viral genome replication

Subcellular Location

Virion

Alternative Nomenclature

helicase NS3 antibody

Non structural protein 4A antibody

Non structural protein 4B antibody

NS3P antibody

NS4A antibody

NS4B antibody

NTPase antibody

p27 antibody

p70 antibody

p8 antibody

Serine protease antibody

General Information

Product

Human Lactoferrin Antibody

Verified Applications

ELISA, ICC/IF, IHC, IP, WB

Host

Chicken

Species Cross Reactivity

Human

Immunogen

Full length native protein purified human Lactoferrin.

Accession #

GeneBank: AAA59511

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.8 µg/µl in antibody stabilization buffer

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

Confocal Microscopy

1:200

DB

1:10,000

ELISA

1:10,000

Immunocytochemistry

1:200

Immunofluorescence

1:200

Immunohistochemistry

1:200

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

P02788

Overview

Iron binding transport proteins which bind two Fe3+ ions in association with the binding of an anion usually bicarbonate. Binds to bacterial surface and is crucial for the bactericidal functions.  Has some antiviral activity against papillomavirus infection.

Molecular Function

DNA binding, Heparin Binding, Iron, metal Binding, Immunity

Subcellular Location

Secreted; Cytoplasmic granule; Nucleus

Expression

Saliva, tears, serum, plasma, urine, distal collecting tubules in the medulla, peripheral blood leukocytes.

Structure

Belongs to transferrin family; Contains 2 transferrin-like domains

Alternative Nomenclature

CKRX antibody

GIG12 antibody

Growth inhibiting protein 12 antibody

HLF2 antibody

Homo sapiens chemokine receptor X antibody

Kaliocin 1 antibody

Lactoferrin antibody

Lactoferroxin A antibody

Lactoferroxin B antibody

Lactoferroxin-C antibody

Lactotransferrin antibody

LF antibody

LTF antibody

Neutrophil lactoferrin antibody

Talalactoferrin alfa antibody

General Information

Product

Zika Virus NS5 Antibody

Description

Affinity Purified RNA-dependent RNA polymerase NS5 Antibody

Verified Applications

ELISA

Host

Rabbit

Species Cross Reactivity

Zika virus

Immunogen

Synthetic pepitde taken within amino acid region 3230-3280 on Zika virus NS5 protein.

Accession #

GenBank:  ALX35659.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55-0.75 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Protein

Uniprot #

O55839

Overview

Viral RNA genome replication

Molecular Function

ATP binding; RNA-directed RNA polymerase activity

Alternative Nomenclature

NS5 zika virus antibody

RNA-dependent RNA polymerase NS5 antibody

nonstructural protein 5 antibody

General Information

Product

Zika Virus Envelope Protein E Antibody

Verified Applications

ELISA

Host

Rabbit

Species Cross Reactivity

Zika Virus

Immunogen

Synthetic peptide taken within amino acid region 280-320 on Zika Virus Envelope Protein E.

Accession #

NCBI:  YP_009227198

Uniprot:  UPI000764CF24

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:10,000

Immunoprecipitation

1:150

Western Blot

1:500