General Information |
|
Product |
TLR5 Positive Control |
Description |
Western Blot Positive Control Toll-like receptor 5 |
Verified Applications |
WB |
Immunogen |
Purified Protein |
|
|
Quantity |
5 Applications |
Volume |
Inquire |
Form |
Western Blot Positive Control |
Storage |
-20⁰C for long term storage |
|
|
Western Blot |
1:500 |
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|
Uniprot # |
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Overview |
Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. |
Molecular Function |
Receptor, interleukin-1 receptor binding, transmembrane signalling receptor activity |
Subcellular Location |
Membrane; Single-pass type I membrane protein |
Expression |
Highly expressed in ovary and in peripheral blood leukocytes, especially in monocytes, less in CD11c+ immature dendritic cells. Also detected in prostate and testis. |
Structure |
Binds MYD88 via their respective TIR domains (By similarity). Homodimer both in the absence and presence of ligand. |
Alternative Nomenclature |
SLEB1 antibody TIL3 antibody Toll like receptor 5 antibody Toll/interleukin 1 receptor like protein 3 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
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TLR-501AP | |||
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TLR5-FITC | |||
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P-TLR5 | |||
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TLR5-BIOTIN | |||
Display accessory details |
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