General Information
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Product
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ULK1 Antibody BIOTIN-Conjugated
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Description
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BIOTIN-Conjugated Serine/Threonine-protein kinase ULK1 Antibody
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Verified Applications
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ELISA, IF, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Bovine, Human, Mouse, Monkey, Panda
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Immunogen
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Synthetic peptide taken within amino acid region 1000-1050 on mouse ULK1 protein.
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Accession #
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NCBI: NP_003556.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.58 µg/µl in antibody stabilization buffer
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Form
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BIOTIN-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:10,000
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Immunofluorescence |
1:100 |
Immunoprecipitation
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1:200
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Western Blot
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1:250
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Protein
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Uniprot #
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O75385
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Overview
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Involved in autophagy in response to starvation. Plays a role early in neuronal differentiation and is required for granule cell axon formation.
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Molecular Function
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ATP Binding, protein serine/threonine kinase activity, Rab GTPase binding, protein complex binding
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Subcellular Location
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Cytoplasm, cytosol, preautphagosomal structure. (Note: under starvation conditions, is localized to puncate structures primarily representing the isolation membrane that sequesters a portion of the cytoplasm resulting in the formation of an autophagosome)
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Expression
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Ubiquitously expressed. Detected in the following adult tissues: skeletal muscle, heart, pancreas, brain, placenta, liver, kidney, and lung.
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Alternative Nomenclature
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ATG1 autophagy related 1 homolog antibody
ATG1A antibody
Autophagy related protein 1 homolog antibody
hATG1 antibody
Serine/threonine-protein kinase ULK1 antibody
ULK1 antibody
Unc 51 like kinase 1 antibody
Unc-51 like kinase 1 (C. elegans) antibody
UNC51 antibody
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