General Information
|
|
Product
|
TDRD1 Peptide
|
Description
|
Antigenic Blocking Peptide Tudor domain-containing protein 1
|
Verified Applications
|
Immunocompeition, Immunodepletion
|
Peptide Description
|
Synthetic Peptide
|
Accession #
|
Gen Bank: BAG65177.1
|
Physical Properties
|
|
Quantity
|
250 µg
|
Volume
|
100 µl
|
Form
|
Antigenic Blocking Peptide
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
Competition/Depletion assay
|
Refer to competition assay protocol
|
Protein
|
Uniprot #
|
Q9BXT4
|
Overview
|
Plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage.
|
Molecular Function
|
metal ion binding
|
Subcellular Location
|
cytoplasm (Note: Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Also present in chromatoid body)
|
Expression
|
Testis and ovary specific. Also expressed in several cancers.
|
Alternative Nomenclature
|
Cancer/testis antigen 41.1 antibody
CT41.1 antibody
FLJ21082 antibody
MTR 1 antibody
Tudor domain containing protein 1 antibody
|
|
|