General Information
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Product
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P2Y12 Antibody FITC-Conjugated
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Description
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FITC-Conjugated P2Y purinoceptor 12 Antibody
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Verified Applications
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CM, ELISA, ICC, IF, IHC, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Chimpanzee, Human, Monkey, Rat
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Immunogen
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Synthetic peptide taken within amino acid region 300-342 on human P2Y12 protein.
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Accession #
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NCBI: NP_795345.1
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.57-0.68 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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FITC-Conjugated
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:10,000
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Immunocytochemistry
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1:100
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Immunofluorescence
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1:100
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Immunohistochemistry
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1:100
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Immunoprecipitation
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1:200
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Western Blot
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1:500
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Protein
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Uniprot #
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Q9H224
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Overview
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Serves as a receptor for ADP and ATP that is coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. It is necessary for platelet aggregation and blood coagulation.
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Molecular Function
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G-protein coupled receptor, Transducer, ADP-receptor activity
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Subcellular Location
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Cell membrane; Multipass membrane protein
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Expression
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It is highly expressed in the platelets with lower levels of expression found in the brain, and is also expressed in the spinal cord and fetal brain. The lowest levels of expression are found in the lung, appendix, pituitary and adrenal gland.
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Alternative Nomenclature
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ADP glucose receptor antibody
ADPG R antibody
BDPLT8 antibody
G protein coupled receptor SP1999 antibody
Gi coupled ADP receptor HORK 3 antibody
HORK3 antibody
P2RY12 antibody
P2T(AC) antibody
P2Y 12 antibody
P2Y purinoceptor 12 antibody
P2Y(12)R antibody
P2Y(AC) antibody
P2Y(ADP) antibody
P2Y(cyc) antibody
P2Y12 antibody
P2Y12 platelet ADP receptor antibody
Purinergic receptor P2RY12 antibody
Purinergic receptor P2Y G protein coupled 12 antibody
Putative G protein coupled receptor antibody
SP1999 antibody
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