General Information |
|
Product |
TLR1 Antibody FITC-Conjugated |
Description |
FITC-Conjugated Toll-like receptor 1 Antibody |
Verified Applications |
ELISA, ICC, IF, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human Predicted: Mouse, Rat
|
Immunogen |
Synthetic peptide taken within amino acid region 370-420 on human Toll-like receptor 1. |
Accession # |
GenBank: AAI09094.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.55-0.67 µg/µl in antibody stabilization buffer |
Immunoglobulin |
IgG |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
ELISA |
1:20,000 |
Immunocytochemistry |
1:100 |
Immunofluorescence |
1:100 |
Immunohistochemistry |
1:100 |
Immunoprecipitation |
1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. |
Molecular Function |
Receptor, Transmembrane signaling receptor activity, triacyl lipopeptide binding |
Subcellular Location |
Cell membrane; Single-pass type I membrane protein, Cytoplasmic vesicle > phagosome membrane; Single-pass type I membrane protein |
Structure |
Binds MYD88 (via TIR domains) (By similarity). Interacts (via extracellular domain) with TLR2. Ligand binding induces the formation of a heterodimer with TLR2 (By similarity). Interacts with CNPY3. |
Alternative Nomenclature |
CD281 antibody CD281 antigen antibody KIAA0012 antibody LPRS5 antibody rsc786 antibody Similar to Drosophila Toll protein antibody TIL antibody TIL. LPRS5 antibody Tlr1 antibody Toll (Drosophila) homolog antibody Toll like receptor 1 antibody Toll like receptor 1 Precursor antibody Toll/Interleukin 1 receptor like antibody Toll/interleukin-1 receptor-like protein antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
TLR-112AP | |||
|
P-TLR1.H | |||
|
TLR1.H-BIOTIN | |||
|
PC-TLR1 | |||
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