General Information
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Product
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N-Chimaerin Peptide
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Description
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Antigenic Blocking Peptide N-Chimaerin isoform 1 Antibody
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Verified Applications
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Immunodepletion, Immunocompetition Assay
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Peptide Description
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Synthetic Peptide
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Accession #
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NCBI: NP_001813
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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P15882
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Overview
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GTPase-activating protein for p21-rac and a phorbol ester receptor. Involved in the assembly of neuronal locomotor circuits as a direct effector of EPHA4 in axon guidance.
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Molecular Function
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GTPase activation
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Subcellular Location
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Cytosol
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Expression
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In neurons in brain regions that are involved in learning and memory processes.
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Structure
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Interacts with EPHA4; effector of EPHA4 in axon guidance linking EPHA4 activation to RAC1 regulation.
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Alternative Nomenclature
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A-chimaerin antibody
Alpha-chimerin antibody
ARHGAP2 antibody
CHN antibody
Chn1 antibody
N chimaerin antibody
NC antibody
Rho GTPase-activating protein 2 antibody
RHOGAP2 antibody
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