General Information
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Product
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FXIIIA Peptide
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Description
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Antigenic Blocking Peptide Blood coagulation factor XIII a subunit C-epitope
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Verified Applications
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Immunodepletion, Immunocompetition
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Peptide Description
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Synthetic peptide taken within amino acid region 700-732 on human factor XIII A subunit protein.
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Accession #
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GenBank: AAA52415.1
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Physical Properties
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Quantity
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250 µg
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Volume
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100 µl
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Form
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Antigenic Blocking Peptide
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Determinant
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C-epitope
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Storage
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-20⁰C for long term storage
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Application Protocol
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Competition/Depletion assay
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Refer to competition assay protocol
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Protein
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Uniprot #
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P00488
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Overview
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Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
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Molecular Function
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Metal ion binding; Protein-glutamine gamma-glutamyltransferase activity
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Subcellular Location
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Cytoplasm. Secreted
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Structure
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Tetramer of two A chains and two B chains.
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Alternative Nomenclature
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bA525O21.1 (coagulation factor XIII, A1 polypeptide) antibody
Coagulation factor XIII A chain antibody
F13A antibody
F13A1 antibody
Fibrin stabilizing factor, A subunit antibody
Fibrinoligase antibody
FSF, A subunit antibody
FXIIIA antibody
Protein-glutamine gamma-glutamyltransferase A chain antibody
TGase antibody
Transglutaminase A chain antibody
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