21 - 30 of 35 results

PDE7B Antibody

Product no.: PD7B-212AP

Description
Publications

General Information
Product	PDE7B Antibody
Description	Affinity Purified cAMP-specific 3',5'-cyclic phosphodiesterase 7B Antibody N-epitope
Verified Applications	CM, ELISA, ICC, IF, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human
Immunogen	Synthetic cyclic peptide common to all PDE7B variants.
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.5 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
Confocal Microscopy	1:200
DB	1:10,000
ELISA	1:10,000
Immunocytochemistry	1:200
Immunofluorescence	1:200
Immunohistochemistry	1:200
Immunoprecipitation	1:250
Western Blot	1:500-1:1,000
Protein
Uniprot #	Q9NP56
Overview	Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain.
Molecular Function	Hydrolase, 3', 5' -cyclic-AMP phosphodiesterase activity
Subcellular Location	Cytosol
Expression	Highly expressed in brain. Also expressed in heart, liver, skeletal muscle and pancreas.
Alternative Nomenclature	bA472E5.1 antibody cAMP specific 3 5 cyclic phosphodiesterase 7B antibody High affinity cAMP specific 3 5 cyclic phosphodiesterase antibody MGC88256 antibody PDE 7B antibody Phosphodiesterase7B antibody RNPDE7B antibody Rolipram insensitive phosphodiesterase type 7 antibody

Protein information supplied by UniProt

Accessories

Product

Note

Status

Price

PDE7B Antibody FITC

PD7B.212-FITC

PDE7B Antibody BIOTIN

PD7B.212-BIOTIN

PDE7B Blocking Peptide

P-PD7B.212

PDE7B Positive Control

PC-PD7B

Display accessory details

Browse these categories as well: cAMP, Phosphodiesterases, Dopamine Receptors, Primaries, Metabolism, Neuroscience

PDE4A Antibody

Product no.: PD4A-112AP

General Information
Product	PDE4A Antibody
Description	Affinity Purified Phosphodiesterase 4A Antibody
Verified Applications	CM, ELISA, ICC, IF, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Moose, Mouse, Rat
Immunogen	Synthetic cyclic peptide corresponding to the C-terminal region of PDE4A. Common to all PDE4A proteins.
Specificity	This antibody labels all known PDE4A variants including PDE4A1 (66 kDa), PDE4A5 (109 kDa), PDE4A8 (106 kDa), AND PDE4Ax (10 kDa) and a 76 kDa testis specific A variant.
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.5 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
Confocal Microscopy	1:100-1:400
DB	1:10,000
ELISA	1:10,000
Immunocytochemistry	1:100-1:400
Immunofluorescence	1:100-1:400
Immunohistochemistry	1:100-1:400
Immunoprecipitation	1:250
Western Blot	1:1,000-1:2,500
Protein
Uniprot #	P27815
Overview	Hydrolyzes the second messenger cAMP which is a key regulator of many important physiological processes.
Molecular Function	cAMP
Subcellular Location	Isoform 1: perinuclear region, Isoform 2: ruffle membrane, Isoform 4: Peripheral membrane protein, Isoform 6: perinuclear region, Isoform 7: Membrane, Cytoplasm
Expression	Isoform 1 is widely expressed. Isoform 2 is abundant in liver, stomach, testis, thyroid and adrenal glands. It is also found in placenta, kidney, pancreas, ovary, uterus, skin, monocytes, mast cells, macrophages, as well as in bronchial smooth muscle. Isoform 6 is expressed at high levels in the heart and small intestine. It is also found in the brain, kidney, spleen, colon, salivary gland, ovary and peripheral blood lympohocytes. Isoform 7 is expressed predominantly in skeletal muscle and brain and at lower levels in the testis. Isoform 7 is expressed in the brain. Found in specific neuronal subpopulations in cortex, spinal cord and cerebellum (at protein level).
Structure	Belongs to cyclic nucleotide phosphodiesterase family. PDE4 subfamily
Alternative Nomenclature	5''-cyclic phosphodiesterase 4A cAMP specific 3 5 cyclic phosphodiesterase 4A DPDE2 dunce like phosphodiesterase E2 PDE 4A PDE4 PDE46 PDE4A11 Phosphodiesterase 4A phosphodiesterase 4A cAMP specific phosphodiesterase E2 dunce homolog phosphodiesterase isozyme 4 phosphodiesterase type 4A11

Protein information supplied by UniProt

FabGennix PDE4A Antibody has been used in 47 Publications

Applications: Confocal microscopy, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunocytochemistry, Immunohistochemistry, and Western blot

Reactivity: Human, Moose, Mouse, and Rat

Avila, Diana V., et al. "Dysregulation of hepatic cAMP levels via altered Pde4b expression plays a critical role in alcohol‐induced steatosis." The Journal of pathology 240.1 (2016).

PMID: 27287961

Applications: Western Blot

Reactivity: Rat

Massimi, Mara, et al. "Increase of Intracellular Cyclic AMP by PDE4 Inhibitors Affects HepG2 Cell Cycle Progression and Survival." Journal of Cellular Biochemistry (2016).

PMID: 27859531

Applications: Western Blot

Reactivity: Human

Kedia, George T., et al. "Expression and Distribution of Phosphodiesterase Isoenzymes in the Human Male Urethra." Urology (2015).

PMID: 25704994

Applications: Immunohistochemistry, Western Blot

Reactivity: Human

Petersen, T. S., et al. "Distribution and function of 3', 5'-Cyclic-AMP phosphodiesterases in the human ovary." Molecular and cellular endocrinology (2015).

PMID: 25578602

Applications: Immunohistochemistry

Reactivity: Human

Guo, Jiejie, et al. "Etazolate abrogates the lipopolysaccharide (LPS)-induced downregulation of the cAMP/pCREB/BDNF signaling, neuroinflammatory response and depressive-like behavior in mice." Neuroscience 263 (2014).

PMID: 24434771

Applications: Western Blot

Reactivity: Mouse

Zhai, Kui, et al. "Phosphodiesterase types 3 and 4 regulate the phasic contraction of neonatal rat bladder smooth myocytes via distinct mechanisms." Cellular signalling 26.5 (2014).

PMID: 23347325

Applications: Western Blot

Reactivity: Rat

Amanda, G. Vang, et al. "Regulatory T-cells and cAMP suppress effector T-cells independently of PKA-CREM/ICER: a potential role for Epac." Biochemical Journal 456.3 (2013).

PMCID: 24007532

Applications: Western Blot

Reactivity: Mouse

Wang, Zhen-Zhen et al. “RNA Interference-Mediated Phosphodiesterase 4D Splice Variants Knock-down in the Prefrontal Cortex Produces Antidepressant-Like and Cognition-Enhancing Effects.” British Journal of Pharmacology 168.4 (2013).

PMCID: 3631387

Applications: Western Blot

Reactivity: Mouse

Yougbaré, Issaka, et al. "NCS 613 Exhibits Anti-Inflammatory Effects On Pbmcs From Lupus Patients By Inhibiting P38 MAPK And NF-Κb Signalling Pathways While Reducing Proinflammatory Cytokine Production." Canadian Journal Of Physiology & Pharmacology 91.5 (2013).

PMCID: 23656347

Applications: Immunocytochemistry, Western Blot

Reactivity: Human

Schaal, Sandra Marie et al. “The Therapeutic Profile of Rolipram, PDE Target and Mechanism of Action as a Neuroprotectant Following Spinal Cord Injury.” Ed. Valentin Ceña. PLoS ONE 7.9 (2012).

PMID: 3446989

Applications: Confocal microscopy, Immunofluorescence, Immunohistochemistry, Western Blot

Reactivity: Rat

Click Here for the complete list of all FabGennix PDE4A Antibody publications

Publishing research using PD4A-112AP? Please let us know, we can cite the reference in this datasheet.

To view the PD4A-112AP specification sheet, click the link below:

FabGennix PD4A-112AP Specification Sheet

Customer ratings for PDE4A Antibody

Number of ratings: 1
Average rating: 5

Excellent
from Verified Customer on 12/10/2020

1:500 dilution in Western blot. Excellent results in Sprague Dawley rats liver tissue.

All incoming ratings are posted by actual shop visitors / webshop customers and their content is checked by the operator by means of a visual inspection.

Accessories

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Note

Status

Price

PDE4A Antibody FITC

PD4A-FITC

PDE4A Antibody BIOTIN

PD4A-BIOTIN

PDE4A Blocking Peptide

P-PD4A

PDE4A Positive Control

PC-PD4A

Display accessory details

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PDE4B Antibody

Product no.: PD4B-201AP

General Information
Product	PDE4B Antibody
Description	Affinity Purified cAMP-specific 3',5'-cyclic phosphodiesterase 4B Antibody N-epitope
Verified Applications	CM, ELISA, ICC, IF, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide common to all PDE4B subtypes taken near N-terminal
Specificity	This antibody detects all PDE4B proteins, including PDE4B1, PDE4B2, PDE4B3, and a 66 kDa PDE4B variant. It does not cross-react with other PDE family members such as PDE4A, PDE4C. PD4B-201AP may have minor crossreactivity to PDE4D. Antibody PD4B-212AP does not have any cross reactivity with any other PDE family members other than: PDE4B1, PDE4B2, PDE4B3, PDE4B4.
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.68 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Determinant	N-epitope
Storage	-20⁰C for long term storage
Application Protocol
Confocal Microscopy	1:250
DB	1:10,000
ELISA	1:10,000
Immunocytochemistry	1:250
Immunofluorescence	1:250
Immunohistochemistry	1:250
Immunoprecipitation	1:350
Western Blot	1:500-1:1,000
Protein
Uniprot #	Q07343
Overview	Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents.
Molecular Function	Hydrolase, 3',5'-cyclic-AMP phosphodiesterase activity, cAMP binding
Expression	Expressed in brain, heart, lung and skeletal muscle.
Alternative Nomenclature	5''-cyclic phosphodiesterase 4B antibody cAMP-specific 3'' antibody cAMP-specific 3',5'-cyclic phosphodiesterase 4B antibody DPDE4 antibody dunce-like phosphodiesterase E4 antibody MGC126529 antibody PDE 4B antibody PDE IVB antibody PDE32 antibody PDE4B5 antibody PDEIVB antibody Phosphodiesterase 4B antibody Phosphodiesterase-4B cAMP-specific (dunce (Drosophila)-homolog) antibody

Protein information supplied by UniProt

Fabgennix PDE4B Antibody has been used in 42 Publications
Kedia, George T., et al. "Expression and Distribution of Phosphodiesterase Isoenzymes in the Human Male Urethra." Urology (2015). PMID25704994	Immunofluorescence, Western Blot; *Human*
Petersen, T. S., et al. "Distribution and function of 3', 5'-Cyclic-AMP phosphodiesterases in the human ovary." Molecular and cellular endocrinology (2015). PMID25578602	Immunohistochemistry; *Human*
Guo, Jiejie, et al. "Etazolate abrogates the lipopolysaccharide (LPS)-induced downregulation of the cAMP/pCREB/BDNF signaling, neuroinflammatory response and depressive-like behavior in mice." Neuroscience 263 (2014): 1-14. PMID24434771	Western Blot; *Mouse*
Zhai, Kui, et al. "Phosphodiesterase types 3 and 4 regulate the phasic contraction of neonatal rat bladder smooth myocytes via distinct mechanisms." Cellular signalling 26.5 (2014): 1001-1010.PMID24463006	Western Blot; *Human*
Hiramoto, Kenichi, et al. "Role of phosphodiesterase 2 in growth and invasion of human malignant melanoma cells." Cellular signalling 26.9 (2014): 1807-1817. PMID24705027	Western Blot; *Rat*
Wang, Zhen-Zhen et al. “RNA Interference-Mediated Phosphodiesterase 4D Splice Variants Knock-down in the Prefrontal Cortex Produces Antidepressant-Like and Cognition-Enhancing Effects.” British Journal of Pharmacology 168.4 (2013): 1001–1014. PMID23003922	Western Blot; *Mouse*
Sanabra, Cristina, Emily M. Johansson, and Guadalupe Mengod. "Critical role for PDE4 subfamilies in the development of experimental autoimmune encephalomyelitis." Journal of chemical neuroanatomy 47 (2013): 96-105. PMID23274837	Immunohistochemistry; *Mouse*
Yougbaré, Issaka, et al. "NCS 613 Exhibits Anti-Inflammatory Effects On Pbmcs From Lupus Patients By Inhibiting P38 MAPK And NF-Κb Signalling Pathways While Reducing Proinflammatory Cytokine Production." Canadian Journal Of Physiology & Pharmacology 91.5 (2013): 353-361. PMID23656347	Immunocytochemistry, Western Blot; *Human*
Haque, Mohammed Z., Paulo S. Caceres, and Pablo A. Ortiz. “β-Adrenergic Receptor Stimulation Increases Surface NKCC2 Expression in Rat Thick Ascending Limbs in a Process Inhibited by Phosphodiesterase 4.” American Journal of Physiology - Renal Physiology 303.9 (2012): F1307–F1314. PMC3518189	Western Blot; *Rat*
Johansson, Emily M., Cristina Sanabra, and Guadalupe Mengod. "Sex‐related differences of cAMP‐specific PDE4B3 mRNA in oligodendrocytes following systemic inflammation." Glia 60.12 (2012): 1815-1825. PMID22848007	Western Blot; *Mouse*

For a complete listing of FabGennix PDE4B publications, please click here.

Publishing research using PD4B-201AP? Please let us know, we can cite the reference in this datasheet.

Could you please provide me with the immunogen sequence for Anti-PDE4B antibody (PD4B-201AP)

If it is not possible to provide me with the immunogen sequence itself, could you please send me the amino acid range that the immunogen is from?

Our PDE4B Antibody (PD4B-201AP), was developed using a recombinant fragment for PDE4B comprising of both UCR1 and UCR2 regions of the long-form variants. The antibody labels all PDE4B variants and has minor cross reactivity to PDE4D. We also have another C-terminal epitope PDE4B selective antibody (PD4B-212AP) that has no cross reactivity to any other PDE4 family members except PDE4B1, PDE4B2, PDE4B3, and PDE4B4.

In addition to these two, we also have antibodies that are selective for PDE4B subtype variants (PDE4B1, PDE4B2, PDE4B3, and PDE4B4) for studying individual variants of the PDE4B family members.

Customer ratings for PDE4B Antibody

Number of ratings: 1
Average rating: 4

Good for western blot
from Anonymous on 12/09/2020

Great results in western blot using rat cell lysate (Mesangial cells). 1/5000 primary antibody dilution for 8 hours.

All incoming ratings are posted by actual shop visitors / webshop customers and their content is checked by the operator by means of a visual inspection.

Accessories

Product

Note

Status

Price

PDE4B Antibody FITC

PD4B-FITC

PDE4B Antibody BIOTIN

PD4B-BIOTIN

PDE4B Blocking Peptide

P-PD4B

PDE4B Positive Control

PC-PD4B

Display accessory details

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PDE4B Positive Control

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PDE4B Antibody

Product no.: PD4B-212AP

Description
Publications

General Information
Product	PDE4B Antibody
Description	Affinity Purified cAMP-specific 3',5'-cyclic phosphodiesterase 4B Antibody C-epitope
Verified Applications	CM, ELISA, ICC, IF, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide common to all PDE4B subtypes taken near C-terminal
Specificity	This antibody detects all PDE4B proteins, including PDE4B1, PDE4B2, PDE4B3, and a 66 kDa PDE4B variant. It does not cross-react with other PDE family members such as PDE4A, PDE4C, or PDE4D.
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.68 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Determinant	C-epitope
Storage	-20⁰C for long term storage
Application Protocol
Confocal Microscopy	1:250
DB	1:10,000
ELISA	1:10,000
Immunocytochemistry	1:250
Immunofluorescence	1:250
Immunohistochemistry	1:250
Immunoprecipitation	1:350
Western Blot	1:500-1:1,000
Protein
Uniprot #	Q07343
Overview	Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory
Molecular Function	Hydrolase, 3',5'-cyclic-AMP phosphodiesterase activity, cAMP binding
Expression	Expressed in brain, heart, lung and skeletal muscle.
Alternative Nomenclature	5''-cyclic phosphodiesterase 4B antibody cAMP-specific 3'' antibody cAMP-specific 3',5'-cyclic phosphodiesterase 4B antibody DPDE4 antibody dunce-like phosphodiesterase E4 antibody MGC126529 antibody PDE 4B antibody PDE IVB antibody PDE32 antibody PDE4B5 antibody PDEIVB antibody Phosphodiesterase 4B antibody Phosphodiesterase-4B cAMP-specific (dunce (Drosophila)-homolog) antibody

Protein information supplied by UniProt

Fabgennix PDE4B Antibody has been used in 42 Publications
Kedia, George T., et al. "Expression and Distribution of Phosphodiesterase Isoenzymes in the Human Male Urethra." Urology (2015). PMID25704994	Immunofluorescence, Western Blot; *Human*
Petersen, T. S., et al. "Distribution and function of 3', 5'-Cyclic-AMP phosphodiesterases in the human ovary." Molecular and cellular endocrinology (2015). PMID25578602	Immunohistochemistry; *Human*
Guo, Jiejie, et al. "Etazolate abrogates the lipopolysaccharide (LPS)-induced downregulation of the cAMP/pCREB/BDNF signaling, neuroinflammatory response and depressive-like behavior in mice." Neuroscience 263 (2014): 1-14. PMID24434771	Western Blot; *Mouse*
Zhai, Kui, et al. "Phosphodiesterase types 3 and 4 regulate the phasic contraction of neonatal rat bladder smooth myocytes via distinct mechanisms." Cellular signalling 26.5 (2014): 1001-1010.PMID24463006	Western Blot; *Human*
Hiramoto, Kenichi, et al. "Role of phosphodiesterase 2 in growth and invasion of human malignant melanoma cells." Cellular signalling 26.9 (2014): 1807-1817. PMID24705027	Western Blot; *Rat*
Wang, Zhen-Zhen et al. “RNA Interference-Mediated Phosphodiesterase 4D Splice Variants Knock-down in the Prefrontal Cortex Produces Antidepressant-Like and Cognition-Enhancing Effects.” British Journal of Pharmacology 168.4 (2013): 1001–1014. PMID23003922	Western Blot; *Mouse*
Sanabra, Cristina, Emily M. Johansson, and Guadalupe Mengod. "Critical role for PDE4 subfamilies in the development of experimental autoimmune encephalomyelitis." Journal of chemical neuroanatomy 47 (2013): 96-105. PMID23274837	Immunohistochemistry; *Mouse*
Yougbaré, Issaka, et al. "NCS 613 Exhibits Anti-Inflammatory Effects On Pbmcs From Lupus Patients By Inhibiting P38 MAPK And NF-Κb Signalling Pathways While Reducing Proinflammatory Cytokine Production." Canadian Journal Of Physiology & Pharmacology 91.5 (2013): 353-361. PMID23656347	Immunocytochemistry, Western Blot; *Human*
Haque, Mohammed Z., Paulo S. Caceres, and Pablo A. Ortiz. “β-Adrenergic Receptor Stimulation Increases Surface NKCC2 Expression in Rat Thick Ascending Limbs in a Process Inhibited by Phosphodiesterase 4.” American Journal of Physiology - Renal Physiology 303.9 (2012): F1307–F1314. PMC3518189	Western Blot; *Rat*
Johansson, Emily M., Cristina Sanabra, and Guadalupe Mengod. "Sex‐related differences of cAMP‐specific PDE4B3 mRNA in oligodendrocytes following systemic inflammation." Glia 60.12 (2012): 1815-1825. PMID22848007	Western Blot; *Mouse*

For a complete listing of FabGennix PDE4B publications, please click here.

Publishing research using PD4B-201AP? Please let us know, we can cite the reference in this datasheet.

Accessories

Product

Note

Status

Price

PDE4B Antibody FITC

PD4B.212-FITC

PDE4B Antibody BIOTIN

PD4B.212-BIOTIN

PDE4B Blocking Peptide

P-PD4B.212

PDE4B Positive Control

PC-PD4B

Display accessory details

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PD4B-201AP

PDE4B Antibody

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Bestrophin Antibody

Product no.: CBEST-141AP

Description

General Information
Product	Bestrophin 1 Antibody
Description	Affinity Purified Bestrophin 1 Antibody
Verified Applications	ELISA, IP, WB
Host	Rabbit
Species Cross Reactivity	Dog, Human, Monkey
Immunogen	Synthetic peptide taken within amino acid region 530-580 on canine Bestrophin 1 protein.
Accession #	NCBI: NP_001091014.1
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.55-0.75 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
DB	1:10,000
ELISA	1:10,000
Immunoprecipitation	1:150
Western Blot	1:500
Protein
Uniprot #	A5H7G8
Overview	Forms calcium sensitive chloride channels. Highly permeable to bicarbonate.
Molecular Function	Ion transport; Sensory transduction; Transport; Vision
Subcellular Location	Cell membrane; Multi-pass membrane protein; Basolateral cell membrane
Expression	Predominantly expressed in the basolateral membrane of the retinal pigment epithelium
Structure	Tetramer or pentamers
Alternative Nomenclature	ARB antibody BEST 1 antibody BEST antibody Best disease antibody Best macular dystrophy antibody Best1V1Delta2 antibody BMD antibody mBest1 antibody RP50 antibody TU15B antibody Vitelliform macular dystrophy 2 antibody Vitelliform macular dystrophy protein 2 antibody VMD 2 antibody

Protein information supplied by UniProt

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Status

Price

Bestrophin Antibody FITC

CBEST-FITC

Bestrophin Antibody BIOTIN

CBEST-BIOTIN

Bestrophin Blocking Peptide

P-CBEST

Bestrophin Positive Control

PC-BEST1

Display accessory details

Browse these categories as well: Vision, Extra Cellular Matrix, Channels & Transporters, Mesenchymal Stem Cells, Lipids, Neuroscience, Primaries

MRGX1 Antibody

Product no.: MRGX1-101AP

Description

General Information
Product	MRGX1 Antibody Affinity Purified
Description	Affinity Purified Mas-related G-protein coupled receptor member X1 Antibody
Verified Applications	ELISA, WB
Host	Rabbit
Species Cross Reactivity	Mouse, Rat
Immunogen	Synthetic peptide taken within amino acid region 280-330 on rat MrgX1 protein.
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.52-0.67 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
DB	1:10,000
ELISA	1:10,000
Western Blot	1:500
Protein
Uniprot #	Q8R4G1
Overview	Orphan receptor activated by neuropeptides terminating in Arg-Phe or Arg-Phe-amide. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system
Molecular Function	G-protein coupled receptor, Receptor, Transducer
Subcellular Location	Cell membrane; Multi-pass membrane protein
Expression	Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons. Associated preferentially with IB4 class of small-diameter somatosensory afferents (also known as nociceptors)
Structure	Belongs to the G-protein coupled receptor 1 family. Mas subfamily
Alternative Nomenclature	G protein coupled receptor MRGX1 antibody G protein coupled receptor SNSR3 antibody GPCR antibody Mas related G protein coupled receptor member X1 antibody MRGPRX1 antibody MRGX1 antibody Sensory neuron specific G protein coupled receptor 3/4 antibody Seven transmembrane helix receptor antibody SNSR3 antibody SNSR4 antibody

Protein information supplied by UniProt

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Price

MRGX1 Antibody FITC

MRGX1-FITC

MRGX1 Antibody BIOTIN

MRGX1-BIOTIN

MRGX1 Blocking Peptide

P-MRGX1

MRGX1 Positive Control

PC-MRGX1

Display accessory details

Browse these categories as well: G-Protein Coupled Receptors, Neuroscience, Sensory Systems, Calcium Binding, Primaries

Npas4 Antibody

Product no.: NPAS4-101AP

Description

General Information
Product	Npas4 Antibody Affinity Purified
Description	Affinity Purified NPAS4 protein Antibody
Verified Applications	ELISA, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide corresponding to unique amino acid sequence on human Npas4 protein.
Accession #	GenBank: AAI43631.1
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.55 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Storage	-20⁰C for long term storage
Application Protocol
DB	1;10,000
ELISA	1;10,000
Western Blot	1:500
Protein
Uniprot #	Q8IUM7
Overview	Acts as a transcriptional activator in the presence of ARNT. Can activate the CME (CNS midline enhancer) element and the expression of the drebrin gene.
Molecular Function	DNA binding;signal transducer activity
Subcellular Location	Nucleus
Expression	Brain.
Alternative Nomenclature	bHLH PAS type transcription factor NXF antibody bHLHe79 antibody Class E basic helix-loop-helix protein 79 antibody HLH-PAS transcription factor NXF antibody Le PAS antibody Neuronal PAS4 antibody NXF antibody PAS domain-containing protein 10 antibody PASD10 antibody

Protein information supplied by UniProt

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Price

Npas4 Antibody FITC

NPAS4-FITC

Npas4 Antibody BIOTIN

NPAS4-BIOTIN

Npas4 Blocking Peptide

P-NPAS4

Npas4 Positive Control

PC-NPAS4

Display accessory details

Browse these categories as well: Transcription, DNA / RNA, Transcription Factors, Neurogenesis & Plasticity, Neuroscience, Primaries

Bestrophin Antibody

Product no.: BEST-101AP

Description
Publications

General Information
Product	Bestrophin Antibody
Description	Affinity Purified Bestrophin 1 Antibody N-epitope
Verified Applications	CM, ELISA, IF, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Mouse, Rat
Immunogen	N-epitope Synthetic peptide corresponding to unique amino acid sequences on human Bestrophin 1 protein.
Accession #	NCBI: NP_004174.1
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.68 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Determinant	N-epitope
Storage	-20⁰C for long term storage
Application Protocol
Confocal Microscopy	1:100
DB	1:10,000
ELISA	1:10,000
Immunocytochemistry	1:100
Immunofluorescence	1:100
Immunohistochemistry	1:100
Immunoprecipitation	1:200
Western Blot	1:500
Protein
Uniprot #	O76090
Overview	Forms calcium sensitive chloride channels. Highly permeable to bicarbonate.
Molecular Function	Ion transport; Sensory transduction; Transport; Vision
Subcellular Location	Cell membrane; Multi-pass membrane protein; Basolateral cell membrane
Expression	Predominantly expressed in the basolateral membrane of the retinal pigment epithelium.
Structure	Tetramer or pentamers
Alternative Nomenclature	ARB antibody BEST 1 antibody BEST antibody Best disease antibody BEST1 antibody Bestrophin1 antibody BMD antibody mBest1 antibody RP50 antibody TU15B antibody Vitelliform macular dystrophy 2 antibody VMD2 antibody

Protein information supplied by UniProt

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Product

Note

Status

Price

Bestrophin Antibody FITC

BEST1.1-FITC

Bestrophin Antibody BIOTIN

BEST1.1-BIOTIN

Bestrophin Blocking Peptide

P-BEST1.1

Bestrophin Positive Control

PC-BEST1

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Bestrophin Antibody

Product no.: BEST-112AP

Description
Publications

General Information
Product	Bestrophin Antibody
Description	Affinity Purified Bestrophin 1 Antibody Mid-Region
Verified Applications	CM, ELISA, IF, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human, Monkey, Rat
Immunogen	Mid-Region Synthetic peptide corresponding to unique amino acid sequences on human Bestrophin 1 protein.
Accession #	NCBI: NP_004174.1
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.65 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Determinant	Mid-Region
Storage	-20⁰C for long term storage
Application Protocol
Confocal Microscopy	1:100
DOT Blot	1:10,000
ELISA	1:10,000
Immunocytochemistry	1:100
Immunofluorescence	1:100
Immunohistochemistry	1:100
Immunoprecipitation	1:200
Western Blot	1:500
Protein
Uniprot #	O76090
Overview	Forms calcium sensitive chloride channels. Highly permeable to bicarbonate.
Molecular Function	Ion transport; Sensory transduction; Transport; Vision
Subcellular Location	Cell membrane; Multi-pass membrane protein; Basolateral cell membrane
Expression	Predominantly expressed in the basolateral membrane of the retinal pigment epithelium
Structure	Tetramer or pentamers
Alternative Nomenclature	ARB antibody BEST 1 antibody BEST antibody Best disease antibody BEST1 antibody Bestrophin1 antibody BMD antibody mBest1 antibody RP50 antibody TU15B antibody Vitelliform macular dystrophy 2 antibody VMD2 antibody

Protein information supplied by UniProt

Accessories

Product

Note

Status

Price

Bestrophin Antibody FITC

BEST1.2-FITC

Bestrophin Antibody BIOTIN

BEST1.2-BIOTIN

Bestrophin Blocking Peptide

P-BEST1.2

Bestrophin Positive Control

PC-BEST1

Display accessory details

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BEST-101AP Bestrophin Antibody	BEST-121AP Bestrophin Antibody	BEST-301AP Bestrophin 3 Antibody
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Bestrophin Antibody

Product no.: BEST-121AP

Description
Publications

General Information
Product	Bestrophin Antibody
Description	Affinity Purified Bestrophin 1 Antibody C-epitope
Verified Applications	CM, ELISA, IF, IHC, IP, WB
Host	Rabbit
Species Cross Reactivity	Human
Immunogen	Synthetic peptide taken within amino acid region 500-585 on human Bestrophin-1 isoform 1 protein.
Specificity	This peptide will label the Bestrophin 1-1 -2, -3, -4, -5 isoforms that are produced by alternate splicing of the C-terminal end.
Accession #	NCBI: NP_004174.1
Physical Properties
Quantity	100 µg
Volume	200 µl
Concentration	0.75 µg/µl in antibody stabilization buffer
Form	Affinity Purified
Clonality	Polyclonal
Determinant	C-epitope
Storage	-20⁰C for long term storage
Application Protocol
Confocal Microscopy	1:100
DOT Blot	1:10,000
ELISA	1:10,000
Immunocytochemistry	1:100
Immunofluorescence	1:100
Immunohistochemistry	1:100
Immunoprecipitation	1:200
Western Blot	1:500
Protein
Uniprot #	O76090
Overview	Forms calcium sensitive chloride channels. Highly permeable to bicarbonate.
Molecular Function	Ion transport; Sensory transduction; Transport; Vision
Subcellular Location	Cell membrane; Multi-pass membrane protein; Basolateral cell membrane
Expression	Predominantly expressed in the basolateral membrane of the retinal pigment epithelium.
Structure	Tetramer or pentamers
Alternative Nomenclature	ARB antibody BEST 1 antibody BEST antibody Best disease antibody BEST1 antibody Bestrophin1 antibody BMD antibody mBest1 antibody RP50 antibody TU15B antibody Vitelliform macular dystrophy 2 antibody VMD2 antibody

Protein information supplied by UniProt