General Information |
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Product |
Inhibin alpha Peptide |
Description |
Antigenic Blocking Peptide Inhibin alpha chain Antibody Mixed Epitope |
Verified Applications |
Immunodepletion, Immunocompetition |
Peptide Description |
Synthetic peptides corresponding to amino acid region taken within 1-50 and 220-270 on Inhibin alpha gene. |
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|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Determinant |
Mixed Epitope |
Storage |
-20⁰C for long term storage |
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Competition/Depletion assay |
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Uniprot # |
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Overview |
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. |
Molecular Function |
Cytokine activity, hormone activity, growth factor activity, receptor binding |
Subcellular Location |
Secreted |
Expression |
Originally found in ovary (granulosa cells) and testis (Sertoli cells), but widely distributed in many tissues including brain and placenta. In adrenal cortex expression is limited to the zona reticularis and the innermost zona fasciculata in the normal gland, extending centripetally into the zona fasciculata in hyperplasia. Also found in adrenocortical tumors. Also expressed in prostate epithelium of benign prostatic hyperplasia, in regions of basal cell hyperplasia and in nonmalignant regions of high grade prostate cancer. Only circulating inhibin B is found in male, whereas circulating inhibins A and B are found in female. |
Alternative Nomenclature |
A inhibin subunit antibody IHA antibody inhA antibody INHA_HUMAN antibody Inhibin alpha chain antibody Inhibin alpha subunit antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
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INBN-141AP | |||
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INBN-141-BIOTIN | |||
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INBN-141-FITC | |||
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PC-INBN | |||
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