General Information
|
|
Product
|
RIC8A Peptide
|
Description
|
Antigenic Blocking Peptide Synembryn-A
|
Verified Applications
|
Immunodepletion, Immunocompetition
|
Peptide Description
|
Synthetic Peptide
|
Accession #
|
NCBI: NP_068751.4
|
Physical Properties
|
|
Quantity
|
250 µg
|
Volume
|
100 µl
|
Form
|
Antigenic Blocking Peptide
|
Storage
|
-20⁰C for long term storage
|
Application Protocol
|
Competition/Depletion assay
|
Refer to competition assay protocol
|
Protein
|
Uniprot #
|
Q9NPQ8
|
Overview
|
Guanine nucleotide exchange factor (GEF) which can activate some G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP.
|
Molecular Function
|
guanyl-nucleotide exchange factor activity, Guanine-nucleotide releasing factor
|
Subcellular Location
|
Interacts with GDP-bound G alpha proteins GNAI1, GNAO1 and GNAQ, and with GNA13 with lower affinity. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.
|
Alternative Nomenclature
|
Protein Ric-8A antibody
resistance to inhibitors of cholinesterase 8 homolog A (C. elegans) antibody
RIC8 antibody
Synembryn-A antibody
|
|
|