General Information |
|
Product |
Histone H3 Antibody FITC-Conjugated |
Description |
FITC-Conjugated Histone H3 Antibody |
Verified Applications |
ELISA, IHC, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Saccharomyces cerevisiae |
Immunogen |
Synthetic peptide taken within amino acid 1-50 on Sacchoromyces cerevisiae protein HH3 protein. |
Accession # |
Gen Bank: EDZ69636.1 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.55-0.75 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
DB |
1:10,000 |
ELISA |
1:10,000 |
Immunohistochemistry | 1:100 |
Immunoprecipitation |
1:150 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. Can bind to DNA (in vitro). |
Molecular Function |
Chromatin regulator, Methyltransferase, Transferase |
Subcellular Location |
Nucleus |
Structure |
Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family. Contains 1 DOT1 domain. |
Alternative Nomenclature |
H3 histone family, member J antibody H3 histone antibody H3 histone family, member A antibody H3 histone family, member B antibody H3 histone family, member C antibody H3 histone family, member D antibody H3 histone family, member F antibody H3 histone family, member H antibody H3 histone family, member I antibody H3 histone family, member K antibody H3 histone family, member L antibody H3 histone, family 3A antibody H3.3A antibody H3F1K antibody H3F3 antibody Histone cluster 1, H3a antibody Histone cluster 1, H3b antibody Histone cluster 1, H3c antibody Histone cluster 1, H3d antibody Histone cluster 1, H3e antibody Histone cluster 1, H3f antibody Histone cluster 1, H3g antibody Histone cluster 1, H3i antibody Histone cluster 1, H3j antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
HH3-312AP | |||
|
P-HH3.312 | |||
|
HH3.312-BIOTIN | |||
|
PC-HH3 | |||
Display accessory details |
Select your currency:
(c) FabGennix International Inc.