General Information |
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Product |
Slingshot homolog 1 Antibody Western Blot Positive Control |
Description |
Western Blot Positive Control Protein phosphatase Slingshot homolog 1 isoform 1 Antibody |
Verified Applications |
WB |
Immunogen |
Purified Protein |
Accession # |
NCBI: NP_061857.3 |
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Quantity |
5 Applications |
Volume |
Inquire |
Form |
Western Blot Positive Control |
Storage |
-20⁰C for long term storage |
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Western Blot |
1:500 |
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Uniprot # |
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Overview |
Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein. |
Molecular Function |
Hydrolase, protein phosphatase |
Subcellular Location |
Cytoplasm, cytoskeleton, cell projection, lamellipodium, cleavage furrow, midbody. (Note: Also recruited to actin rich membrane protrusions such as lamellipodia, which may allow local control of actin dynamics at site of cell locomotion. Also localized to |
Alternative Nomenclature |
AW551225 antibody Coro1c antibody coronin, actin binding protein 1C antibody Gm1394 antibody Gm1395 antibody Protein phosphatase Slingshot homolog 1 antibody slingshot like 1 antibody SSH1 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
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SISHT-101AP | |||
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SISHT-FITC | |||
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P-SISHT | |||
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SISHT-BIOTIN | |||
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