General Information

Product

FOLR2 Antibody

Description

Affinity Purified Folate receptor beta Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1-50 on rat Folate receptor 2 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:500

Protein

Uniprot #

D4A4S5

Overview

Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release.

Molecular Function

Receptor

Subcellular Location

Cell membrane; Lipidanchor > GPI-anchor, Secreted

Expression

Expressed in placenta and hematopoietic cells. Expression is increased in malignant tissues.

Structure

Belongs to the folate receptor family.

Alternative Nomenclature

beta hFR antibody
FBP antibody
FBP/PL 1 antibody
FBP2 antibody
fetal/placental antibody
folate receptor 2 (fetal) antibody
Folate receptor 2 antibody
Folate receptor antibody
Folate receptor beta antibody
Folate receptor, fetal/placental antibody
Folbp 2 antibody
Folr2 antibody
FR beta antibody
FR P3 antibody
Placental folate binding protein antibody

General Information

Product

LRRK1 Antibody

Description

Affinity Purified Leucine-rich repeat serine/threonine-protein kinase 1 Antibody

Verified Applications

ELISA, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1950-2015 on human Leucine-rich repeat serine/threonine-protein kinase 1  protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5-1.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:2,500-1:5,000

Protein

Uniprot #

Q38SD2

Overview

ATP + a protein = ADP + a phosphoprotein.

Molecular Function

ATP binding

GTP binding

identical protein binding

metal ion binding

protein serine/threonine kinase activity

signal transducer activity

Subcellular Location

Cytoplasm

Expression

Homodimer.

Structure

Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily.

Alternative Nomenclature

KIAA1790 antibody

Leucine rich repeat serine/threonine protein kinase 1 antibody

Lrrk1 antibody

RIPK6 antibody

Roco1 antibody

General Information

Product

RBP2 Antibody

Description

Affinity Purified Retinol-Binding Protein 4 Receptor 2 / RBP4 receptor 2 / STRA6 - Like Protein Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 200-250 on mouse Retinol-Binding Protein 4 Receptor 2 / RBP4 receptor 2 / STRA6 - Like Protein.

Accession #

NCBI:  MGI 1921402

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5-1.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:2,500-1:5,000

Protein

Uniprot #

Q9DBN1

Overview

retinol transport

vitamin A import

Molecular Function

Plasma Membrane

Subcellular Location

Highly expressed in liver and small intestine. Also expressed in spleen, kidney, colon, stomach, placenta, adipose tissue and isolated adipocytes.

Structure

Retinol-Binding Protein 4 Receptor 2 / RBP4 receptor 2 / STRA6 - Like Protein

Alternative Nomenclature

Cellular retinol binding protein II antibody

CRABP II antibody

Crbp 2 antibody

CRBP II antibody

CrbpII antibody

Rbp2 antibody

RBPC2 antibody

Retinol binding protein 2 antibody

Retinol binding protein 2 cellular antibody

General Information

Product

DAP Kinase 1 Antibody

Description

Affinity Purified Death-associated protein kinase 1 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region 1370-1420 on human Death-associated protein kinase 1 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5-1.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:2,500-1:5,000

Protein

Uniprot #

P53355

Overview

Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy.

Molecular Function

ATP binding

calmodulin binding

calmodulin-dependent protein kinase activity

GTP binding

identical protein binding

protein kinase activity

protein serine/threonine kinase activity

syntaxin-1 binding

Subcellular Location

Cytoskeleton

Expression

Isoform 2 is expressed in normal intestinal tissue as well as in colorectal carcinomas.

Structure

The autoinhibitory domain sterically blocks the substrate peptide-binding site by making both hydrophobic and electrostatic contacts with the kinase core.

Alternative Nomenclature

DAK1 antibody

DAP K1 antibody

DAP kinase 1 antibody

DAPK antibody

DAPK1 antibody

Death Associated Protein Kinase 1 antibody

General Information

Product

ZIP Kinase Antibody

Description

Affinity Purified Death-associated protein kinase 3 Antibody

Verified Applications

ELISA, IHC, IP, WB

Host

Rabbit

Species Cross Reactivity

Mouse, Rat

Immunogen

Synthetic peptide taken within amino acid region on 400-448 on mouse Death-associated protein kinase 3 protein.

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.5-1.5 µg/µl in antibody stabilization buffer

Immunoglobulin

IgG

Form

Affinity Purified

Purification Method

Immobilized antigen affinity chromatography

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

ELISA

1:50,000

Immunoprecipitation

1:200

Western Blot

1:2,500-1:5,000

Protein

Uniprot #

O54784

Overview

Serine/threonine kinase which is involved in the regulation of apoptosis, autophagy, transcription, translation and actin cytoskeleton reorganization.

Molecular Function

ATP binding

identical protein binding

kinase activity

leucine zipper domain binding

protein C-terminus binding

protein homodimerization activity

protein serine/threonine kinase activity

Rho GTPase binding

Subcellular Location

Cytoskeleton, Nucleus

Expression

Highly expressed in heart, brain, lung, skeletal muscle, kidney and testis. Lower levels in liver and spleen.

Structure

Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.

Alternative Nomenclature

DAP kinase 3 antibody

DAP like kinase antibody

DAPK3 antibody

Death associated kinase 3 antibody

Death associated protein kinase 3 antibody

Dlk antibody

MYPT1 kinase antibody

ZIP antibody

ZIP kinase antibody

ZIP kinase isoform antibody

ZIPK antibody

zipper-interacting protein kinase antibody