General Information |
|
Product |
Epac2 Peptide |
Description |
Antigenic Blocking Peptide Rap Guanine Nucleotide Exchange Factor 3 |
Verified Applications |
Immunocompetition, Immunodepletion |
Peptide Description |
Synthetic peptide corresponding to amino acids 743-762 of Epac2 protein.
CPREQFDSLTPLPEQEGPT |
|
|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Storage |
-20⁰C for long term storage |
|
|
Competition/Depletion assay |
|
|
|
Uniprot # |
|
Overview |
Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2 (By similarity). |
Molecular Function |
Guanine-nucleotide releasing factor |
Subcellular Location |
Cytoplasm; Membrane; Peripheral membrane protein |
Structure |
Interacts with RIMS1 and RIMS2. Probably part of a complex with RIMS2 and GTP-activated RAB3A (By similarity). |
Alternative Nomenclature |
CAMP GEFII antibody cAMP regulated guanine nucleotide exchange factor II antibody CGEF2 antibody Epac 2 antibody Exchange protein directly activated by cAMP 2 antibody Nbla00496 antibody Putative protein product of Nbla00496 antibody Rap guanine nucleotide exchange factor (GEF) 4 antibody RAPGEF 4 antibody |
Protein information supplied by UniProt
Fabgennix Epac2 Antibody has been used in 1 Publication |
|
McPartlin, L.A., P.E. Visconti, and S.J. Bedford-Guaus. “Guanine-Nucleotide Exchange Factors (RAPGEF3/RAPGEF4) Induce Sperm Membrane Depolarization and Acrosomal Exocytosis in Capacitated Stallion Sperm.”Biology of Reproduction 85.1 (2011): 179–188. PMC3123385
|
Confocal Microscopy, Immunofluorescence, Western Blot; Horse, Mouse |
Publishing research using EPAC-201AP? Please let us know, we can cite the reference in this datasheet.
Product | Note | Status | Price | |
---|---|---|---|---|
|
EPAC-201AP | |||
|
EPAC2-FITC | |||
|
EPAC2-BIOTIN | |||
|
PC-EPAC2 | |||
Display accessory details |
Select your currency:
(c) FabGennix International Inc.