General Information
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Product
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MYLK2 Antibody BIOTIN
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Description
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BIOTIN-Conjugated Myosin light chain kinase 2 Antibody
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Verified Applications
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ELISA, IP, WB
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Host
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Rabbit
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Species Cross Reactivity
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Human
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Immunogen
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Synthetic peptide taken within aino acid region 200-250 on human Myosin light chain kinase 2 protein.
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Physical Properties
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Quantity
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100 µg
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Volume
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200 µl
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Concentration
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0.5-1.5 µg/µl in antibody stabilization buffer
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Immunoglobulin
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IgG
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Form
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BIOTIN-Conjugated
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Purification Method
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Immobilized antigen affinity chromatography
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Clonality
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Polyclonal
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Storage
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-20⁰C for long term storage
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Application Protocol
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ELISA
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1:50,000
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Immunoprecipitation
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1:200
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Western Blot
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1:2,500-1:5,000
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Protein
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Uniprot #
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Q9H1R3
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Overview
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Implicated in the level of global muscle contraction and cardiac function. Phosphorylates a specific serine in the N-terminus of a myosin light chain.
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Molecular Function
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ATP binding
calmodulin binding
calmodulin-dependent protein kinase activity
myosin light chain kinase activity
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Subcellular Location
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Cytoplasm
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Expression
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Heart and skeletal muscles. Increased expression in the apical tissue compared to the interventricular septal tissue.
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Structure
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Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
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Alternative Nomenclature
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KMLC antibody
MLCK antibody
MLCK2 antibody
MYLK 2 antibody
Myosin light chain kinase 2 antibody
MYOSIN LIGHT POLYPEPTIDE KINASE antibody
Myosin light polypeptide kinase, skeletal/cardiac antibody
skeletal/cardiac muscle antibody
skMLCK antibody
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